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Hemosiderosis, Pulmonary

Disease ID: disease_node_904

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DbxrefICD10CM:J84.03, ICD9CM:516.1, MESH:D000097545, MIM:178550, MIM:235500, ORDO:99931, SNOMEDCT_US_2023_03_01:190848001, UMLS_CUI:C0020807
SubclassofDOID_12119, DOID_850
Data SourceDOID, MESH
SynonymsIdiopathic pulmonary hemosiderosis, brown induration, brown lung
Disease Has LocationUBERON_0002048
Mesh IdD000097545
Mesh LabelHemosiderosis, Pulmonary
Mesh SubclassofD006486, D008171
Doid Labelpulmonary hemosiderosis
Doid DescriptionA lung disease with an unknown etiology affecting the lungs which results in bleeding from tiny alveolar capillaries. Examination of sputum and bronchoalveolar lavage fluid can disclose hemosiderin-laden alveolar macrophages (siderophages), and the lung biopsy shows numerous siderophages in the alveoli. Alveolar hemorrhage is characterized by hemoptysis, shortness of breath, alveolar infiltrates on chest radiograph, and various degrees of anaemia. Following a bleeding episode, the alveolar macrophages convert the hemoglobin's iron into hemosiderin within 36-72h. MESH C536281 obsoleted in 2024.[LS]
Has SymptomSYMP_0019153, SYMP_0000007
Disease Node Iddisease_node_904
Doid IdDOID_12118
LabelHemosiderosis, Pulmonary
Doid Alternate IdsDOID_0050330