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Sjogren-Larsson Syndrome

Disease ID: disease_node_8580

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DbxrefGARD:7654, MESH:D016111, MIM:270200, NCI:C85070, ORDO:816, SNOMEDCT_US_2023_03_01:111303009, UMLS_CUI:C0037231
SubclassofDOID_225, DOID_0050737
Data SourceDOID, MESH
SynonymsFALDH deficiency, SLS, Sjogren Larsson syndrome, Sjogren-Larsson's syndrome, fatty acid alcohol oxidoreductase deficiency
Mesh IdD016111
Mesh LabelSjogren-Larsson Syndrome
Mesh SubclassofD008064, D012873, D007057
Doid LabelSjogren-Larsson syndrome
Doid DescriptionA syndrome that is characterized by ichthyosis, mental retardation, spastic paraparesis, macular dystrophy, and leukoencephalopathy, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the aldehyde dehydrogenase 3 family member A2 (ALDH3A2) gene, which encodes fatty aldehyde dehydrogenase, on chromosome 17p11. OMIM mapping confirmed by DO. [LS].
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_8580
Doid IdDOID_14501
LabelSjogren-Larsson Syndrome