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Wolman Disease

Disease ID: disease_node_8145

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DbxrefGARD:7899, ICD10CM:E75.5, MESH:D015223, MIM:620151, NCI:C61271, ORDO:75233, SNOMEDCT_US_2023_03_01:82500001, UMLS_CUI:C0043208
SubclassofDOID_0080217
Data SourceDOID, MESH
SynonymsAcid esterase deficiency, Acid lipase deficiency, Wolman xanthomatosis, Wolman's disease, Wolman's or triglyceride storage type III disease, Xanthomatosis, familial, acute infantile lysosomal acid lipase deficiency, complete LAL deficiency, complete LIPA deficiency, complete cholesterol ester hydrolase deficiency, complete lysosomal acid lipase deficiency
Mesh IdD015223
Mesh LabelWolman Disease
Mesh SubclassofD015217, D007232
Doid LabelWolman disease
Doid DescriptionA lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life.
Disease Node Iddisease_node_8145
Doid IdDOID_14497
LabelWolman Disease