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Rothmund-Thomson Syndrome

Disease ID: disease_node_6205

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DbxrefGARD:4392, ICD10CM:Q82.8, MESH:D011038, MIM:268400, NCI:C3335, SNOMEDCT_US_2023_03_01:205572001, UMLS_CUI:C0032339
SubclassofDOID_37
Data SourceDOID, MESH
SynonymsCongenital poikiloderma, RTS
Mesh IdD011038
Mesh LabelRothmund-Thomson Syndrome
Mesh SubclassofD049914, D012868, D012873, D007232
Doid LabelRothmund-Thomson syndrome
Doid DescriptionA skin disease characterized by poikiloderma, congenital bone defects, and an increased risk of osteosarcoma in childhood and skin cancer later in life that has_material_basis_in homozygous or compound heterozygous mutation in the DNA helicase gene RECQL4 on chromosome 8q24. OMIM mapping confirmed by DO. [SN].
Disease Node Iddisease_node_6205
Doid IdDOID_2732
LabelRothmund-Thomson Syndrome