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Papillon-Lefevre Disease

Disease ID: disease_node_5863

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DbxrefGARD:3100, MESH:D010214, MIM:245000, NCI:C84992, ORDO:678, SNOMEDCT_US_2023_03_01:40158001, UMLS_CUI:C0030360
SubclassofDOID_0050737, DOID_2121, DOID_1091
Data SourceDOID, MESH
SynonymsPapillon Lefevre syndrome, Papillon-Lefvre syndrome
Disease Has LocationUBERON_0001091
Mesh IdD010214
Mesh LabelPapillon-Lefevre Disease
Mesh SubclassofD007645
Doid LabelPapillon-Lefevre disease
Doid DescriptionAn ectodermal dysplasia that is characterized by palmoplantar keratoderma associated with early-onset periodontitis and has_material_basis_in homozygous or compound heterozygous mutation in the cathepsin C gene on chromosome 11q14. OMIM mapping confirmed by DO. [SN].
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_5863
Doid IdDOID_3389
LabelPapillon-Lefevre Disease