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Leukoencephalopathy, Progressive Multifocal

Disease ID: disease_node_4728

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DbxrefGARD:7468, ICD10CM:A81.2, ICD9CM:046.3, MESH:D007968, NCI:C26815, SNOMEDCT_US_2023_03_01:22255007, UMLS_CUI:C0023524
SubclassofDOID_934
Data SourceDOID, MESH
SynonymsPML
Mesh IdD007968
Mesh LabelLeukoencephalopathy, Progressive Multifocal
Mesh SubclassofD056784, D018792, D012897, D027601, D003711
Doid Labelprogressive multifocal leukoencephalopathy
Doid DescriptionA viral infectious disease that involves reactivation of JC polyomavirus in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma.
Has PhenotypeHP_0100543
Has SymptomSYMP_0000508, SYMP_0000293, SYMP_0000605, SYMP_0000414
Has Material Basis InNCBITaxon_10632
Disease Node Iddisease_node_4728
Doid IdDOID_643
LabelLeukoencephalopathy, Progressive Multifocal