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Craniofacial Dysmorphism, Skeletal Anomalies, And Impaired Intellectual Development Syndrome 1

Disease ID: disease_node_20274

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DbxrefMIM:213980
SubclassofDOID_0050737, DOID_0081072
Data SourceDOID
Doid Labelcraniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 1
Doid DescriptionA craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome that is characterized by cranial involvement with macrocrania at birth, brachycephaly, anomalies of middle fossa structures including hypoplasia of corpus callosum, enlargement of septum pellucidum, and dilated lateral ventricles, as well as cortical atrophy and hypodensity of the gray matter and that has_material_basis_in homozygous mutation in the TMCO1 gene on chromosome 1q24.
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_20274
Doid IdDOID_0081124
LabelCraniofacial Dysmorphism, Skeletal Anomalies, And Impaired Intellectual Development Syndrome 1