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Hypomyelinating Leukodystrophy 4

Disease ID: disease_node_19946

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DbxrefICD10CM:E75.2, MIM:612233, ORDO:280288
SubclassofDOID_0060786, DOID_0050737
Data SourceDOID
SynonymsHLD4, MitCHAP60 disease, Pelizaeus-Merzbacher-like disease due to HSPD1 mutation, mitochondrial HSP60 chaperonopathy
Doid Labelhypomyelinating leukodystrophy 4
Doid DescriptionA hypomyelinating leukodystrophy characterized by autosomal recessive inheritance of hypotonia, nystagmus, psychomotor developmental delay, and severe hypomyelinating leukoencephalopathy that has_material_basis_in homozygous mutation in the HSPD1 gene on chromosome 2q33.
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_19946
Doid IdDOID_0060789
LabelHypomyelinating Leukodystrophy 4