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Lissencephaly 9 With Complex Brainstem Malformation

Disease ID: disease_node_19274

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DbxrefMIM:618325, ORDO:572013
SubclassofDOID_0050736, DOID_0050453
Data SourceDOID
SynonymsLIS9, posterior-predominant lissencephaly-broad flat pons and medulla-midline crossing defects syndrome
Doid Labellissencephaly 9 with complex brainstem malformation
Doid DescriptionA lissencephaly characterized by global developmental delay, impaired intellectual development with poor or absent speech, pachygyria, lissencephaly, and malformation of the brainstem that has_material_basis_in heterozygous mutation in the MACF1 gene on chromosome 1p34.3.
Has Material Basis InGENO_0000147
Disease Node Iddisease_node_19274
Doid IdDOID_0112228
LabelLissencephaly 9 With Complex Brainstem Malformation