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Methylmalonic Aciduria And Homocystinuria Type Cblc

Disease ID: disease_node_19192

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DbxrefMIM:277400
SubclassofDOID_14749, DOID_0080578
Data SourceDOID
SynonymsCobalamin C deficiency, MAHCC
Doid Labelmethylmalonic aciduria and homocystinuria type cblC
Doid DescriptionA methylmalonic acidemia that has_material_basis_in deficiency in synthesis of both AdoCbl and MeCbl (cblC) and is characterized by decreased levels of the coenzymes adenosylcobalamin (AdoCbl) and methylcobalamin (MeCbl), which results in decreased activity of the respective enzymes methylmalonyl-CoA mutase.
Has Material Basis InGENO_0000930
Disease Node Iddisease_node_19192
Doid IdDOID_0050715
LabelMethylmalonic Aciduria And Homocystinuria Type Cblc