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Congenital Myopathy 1B

Disease ID: disease_node_18955

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DbxrefGARD:10316, MIM:255320, ORDO:598
SubclassofDOID_0081337
Data SourceDOID
Synonymsmultiminicore disease
Doid Labelcongenital myopathy 1B
Doid DescriptionA congenital myopathy that is characterized by multiple areas of reduced mitochondrial oxidative activity running along a limited extent of the longitudinal axis of the muscle fiber, so-called 'minicores' and that has_material_basis_in homozygous or compound heterozygous mutation in the RYR1 gene on chromosome 19q13. Multiminocore disease is broadly classified into four groups: classic form, moderate form with hand involvement, antenatal form with arthrogryposis multiplex congenita, and ophthalmoplegic form.
Disease Node Iddisease_node_18955
Doid IdDOID_0080991
LabelCongenital Myopathy 1B