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Congenital Myopathy 20

Disease ID: disease_node_18953

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DbxrefMIM:620310
SubclassofDOID_0050737, DOID_0081337
Data SourceDOID
Doid Labelcongenital myopathy 20
Doid DescriptionA congenital myopathy that has_material_basis_in homozygous or compound heterozygous mutation in the RYR3 gene on chromosome 15q13 and that shows wide phenotypic variability. Some patients present in early childhood with proximal muscle weakness affecting the lower and upper limbs resulting in difficulties running and climbing, whereas others present soon after birth with congenital limb or distal contractures.
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_18953
Doid IdDOID_0081352
LabelCongenital Myopathy 20