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Congenital Myopathy 2C

Disease ID: disease_node_18948

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DbxrefMIM:620278
SubclassofDOID_0050736, DOID_0081337
Data SourceDOID
Doid Labelcongenital myopathy 2C
Doid DescriptionA congenital myopathy that is characterized by severe congenital weakness usually resulting in death from respiratory failure in the first year or so of life and that has_material_basis_in heterozygous mutation in the ACTA1 gene on chromosome 1q42. Heterozygous mutation in the ACTA1 gene can also cause autosomal domit typical congenital myopathy-2A (CMYP2A). Biallelic mutation in the ACTA1 gene causes autosomal recessive severe infantile congenital myopathy-2B (CMYP2B).
Has Material Basis InGENO_0000147
Disease Node Iddisease_node_18948
Doid IdDOID_0081340
LabelCongenital Myopathy 2C