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Congenital Myopathy 8

Disease ID: disease_node_18946

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DbxrefMIM:618654
SubclassofDOID_0050736, DOID_0081337
Data SourceDOID
Doid Labelcongenital myopathy 8
Doid DescriptionA congenital myopathy that is characterized by hypotonia and delayed motor development apparent from infancy or childhood, resulting in difficulties walking or loss of ambulation within the first few decades and that has_material_basis_in heterozygous mutation in the ACTN2 gene on chromosome 1q43. Heterozygous mutation in the ACTN2 gene can also cause distal myopathy-6 (MPD6), which shows later onset and is less severe.
Has Material Basis InGENO_0000147
Disease Node Iddisease_node_18946
Doid IdDOID_0081342
LabelCongenital Myopathy 8