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Immunodeficiency 62

Disease ID: disease_node_17346

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DbxrefMIM:618459, UMLS_CUI:C5193109
SubclassofDOID_0050737, DOID_2115
Data SourceDOID
SynonymsIMD62
Doid Labelimmunodeficiency 62
Doid DescriptionA B cell deficiency characterized by onset late in the first decade of life of recurrent upper and lower respiratory infections, impaired antibody response to vaccination, low levels of circulating memory B cells, and almost undetectable antibodies that has_material_basis_in homozygous or compound heterozygous mutation in the ARHGEF1 gene on chromosome 19q13.2.
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_17346
Doid IdDOID_0111991
LabelImmunodeficiency 62