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Dystonia 32

Disease ID: disease_node_17271

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DbxrefMIM:619637
SubclassofDOID_543, DOID_0050737
Data SourceDOID
SynonymsDYT32
Doid Labeldystonia 32
Doid DescriptionA dystonia characterized by onset of symptoms in adulthood, sustained or intermittent muscle contractions causing abnormal movements or posturing. The disorder is slowly progressive with eventual generalized involvement of the limbs, trunk, neck, and larynx, resulting in dysarthria and dysphagia. Brain imaging may show abnormalities in the basal ganglia that has_material_basis_in homozygous mutation in the VPS11 gene on chromosome 11q23.
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_17271
Doid IdDOID_0060939
LabelDystonia 32