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17-Beta Hydroxysteroid Dehydrogenase 3 Deficiency

Disease ID: disease_node_17168

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DbxrefGARD:5659, MIM:264300, ORDO:752
SubclassofDOID_3765, DOID_0050737
Data SourceDOID
Synonyms17-KSR deficiency, 17-beta-hydroxysteroid dehydrogenase 3 deficiency, 17-ketoreductase deficiency, 17-ketosteroidreductase deficiency, 46,XY disorder of sex development due to 17-beta-hydroxysteroid dehydrogenase 3 deficiency, male pseudohermaphroditism with gynecomastia, neutral 17-beta-hydroxysteroid oxidoreductase deficiency
Doid Label17-beta hydroxysteroid dehydrogenase 3 deficiency
Doid DescriptionA pseudohermaphroditism characterized by undermasculinization in males including hypoplastic-to-normal internal genitalia with female external genitalia and the absence of a prostate, impaired testicular synthesis of testosterone resulting in insufficient formation of dihydrotestosterone during fetal development and resulting in pseudohermaphroditism in males that has_material_basis_in homozygous or compound heterozygous mutation of the HSD17B3 gene on chromosome 9q22.
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_17168
Doid IdDOID_0112248
Label17-Beta Hydroxysteroid Dehydrogenase 3 Deficiency