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X-Linked Dyserythropoietic Anemia

Disease ID: disease_node_17081

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DbxrefMIM:300835, ORDO:363727
SubclassofDOID_0080012, DOID_2355
Data SourceDOID
SynonymsX-linked anemia with/without neutropenia and/or platelet abnormalities, X-linked dyserythropoietic anemia with abnormal platelets and neutropenia
Doid LabelX-linked dyserythropoietic anemia
Doid DescriptionAn anemia characterized by early-onset anemia and bone marrow erythroid hypoplasia with variable neutropenia that has_material_basis_in hemizygous splice-site mutation in the GATA1 gene on chromosome Xp11.23. This mutaion impairs expression of the long isoform of GATA1 but expression of a short form is seen.
Has Material Basis InGENO_0000149
Disease Node Iddisease_node_17081
Doid IdDOID_0112156
LabelX-Linked Dyserythropoietic Anemia