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Primary Hypoalphalipoproteinemia 2

Disease ID: disease_node_16842

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DbxrefGARD:758, MIM:618463, ORDO:425
SubclassofDOID_1387
Data SourceDOID
SynonymsApolipoprotein A-I deficiency
Doid Labelprimary hypoalphalipoproteinemia 2
Doid DescriptionA hypolipoproteinemia that is characterized by dysfunctional apoA-I production, resulting in undetectable levels of apoA-I in serum and in markedly low levels of serum high density lipoprotein cholesterol, is generally an autosomal recessive disorder associated with extensive atherosclerosis, xanthomas, and corneal opacities, and that has_material_basis_in homozygous, compound heterozygous, or heterozygous mutation in the APOA1 gene on chromosome 11q23.
Disease Node Iddisease_node_16842
Doid IdDOID_0080958
LabelPrimary Hypoalphalipoproteinemia 2