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Multiple Mitochondrial Dysfunctions Syndrome 2

Disease ID: disease_node_16814

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DbxrefGARD:12632, MIM:614299, ORDO:401874
SubclassofDOID_0050737, DOID_0070330
Data SourceDOID
SynonymsBOLA3 deficiency, multiple mitochondrial dysfunctions syndrome 2 with hyperglycinemia
Doid Labelmultiple mitochondrial dysfunctions syndrome 2
Doid DescriptionA multiple mitochondrial dysfunctions syndrome that is characterized by increased serum glycine and lactate, developmental regression in infancy, an encephalopathic disease course with seizures, spasticity, loss of head control, and abnormal movement, and has_material_basis_in autosomal recessive inheritance of homozygous mutation in the bolA family member 3 gene on chromosome 2p13.
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_16814
Doid IdDOID_0080134
LabelMultiple Mitochondrial Dysfunctions Syndrome 2