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Isolated Microphthalmia 5

Disease ID: disease_node_16610

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DbxrefICD10CM:Q15.8, MIM:611040, ORDO:251279
SubclassofDOID_0050737, DOID_0080637
Data SourceDOID
SynonymsMCOP5, microphthalmia-retinitis pigmentosa-foveoschisis-optic disc drusen syndrome, posterior microphthalmia with retinitis pigmentosa, foveoschisis and optic disc drusen
Doid Labelisolated microphthalmia 5
Doid DescriptionAn isolated microphthalmia characterized by autosomal recessive inheritance of posterior microphthalmia, hypermetropia, night blindness, decreased visual acuity, reduced macular reflex, scleral thickening, impared rod and cone responses on ERG, foveoschisis and in some patients retinal pigment epithelium atrophy, arteriolar attenuation, angle-closure glaucoma and optic disc drusen that has_material_basis_in homozygous or compound heterozygous mutation in the MFRP gene on chromosome 11q23.
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_16610
Doid IdDOID_0060837
LabelIsolated Microphthalmia 5