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Acrofacial Dysostosis Cincinnati Type

Disease ID: disease_node_15740

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DbxrefMIM:616462
SubclassofDOID_0050736, DOID_0060379
Data SourceDOID
Doid Labelacrofacial dysostosis Cincinnati type
Doid DescriptionAn acrofacial dysostosis characterized by a spectrum of mandibulofacial dysostosis phenotypes, such as cleft palate, micrognathia, malar flattening, microcephaly and, in some cases, extrafacial skeletal defects. It is that has_material_basis_in heterozygous mutation in the POLR1A gene on chromosome 2p11.
Has PhenotypeHP_0000272, HP_0000347
Has Material Basis InGENO_0000147
Disease Node Iddisease_node_15740
Doid IdDOID_0060353
LabelAcrofacial Dysostosis Cincinnati Type