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Chondrodysplasia With Joint Dislocations Gpapp Type

Disease ID: disease_node_15641

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DbxrefGARD:11009, MIM:614078, ORDO:280586
SubclassofDOID_2256, DOID_0050737
Data SourceDOID
SynonymsgPAPP deficiency
Doid Labelchondrodysplasia with joint dislocations gPAPP type
Doid DescriptionAn osteochondrodysplasia characterized by prenatal onset of disproportionate short stature, shortening of the limbs, joint hyperlaxity and/or dislocations, micrognathia, cleft palate, brachydactyly, short metacarpals, supernumerary carpal ossification centers and dysmorphic facial features that has_material_basis_in homozygous or compound heterozygous mutation in the IMPAD1 gene on chromosome 8q12.
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_15641
Doid IdDOID_0112224
LabelChondrodysplasia With Joint Dislocations Gpapp Type