Bn2 Diffuse Large B-Cell Lymphoma
Disease ID: disease_node_15578
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| Dbxref | NCI:C148395 |
|---|---|
| Subclassof | DOID_0050745 |
| Data Source | DOID |
| Synonyms | BN2 DLBCL |
| Doid Label | BN2 diffuse large B-cell lymphoma |
| Doid Description | A diffuse large B-cell lymphoma that is categorized as BN2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and BN2 DLBCLs often, but do not always, have a translocation involving the BCL6 locus and/or some combination of mutations affecting NOTCH2, TNFAIP3, BCL10 and UBE2A. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting CD70, which can be coding or non-coding. |
| Disease Node Id | disease_node_15578 |
| Doid Id | DOID_0081064 |
| Label | Bn2 Diffuse Large B-Cell Lymphoma |
- Outgoing r'ship
SUBCLASS_OFto/from Lymphoma, Large B-Cell, Diffuse(ID:disease_node_8702) (Disease)