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Mcd Diffuse Large B-Cell Lymphoma

Disease ID: disease_node_15574

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DbxrefNCI:C148394
SubclassofDOID_0050745
Data SourceDOID
SynonymsMCD DLBCL
Doid LabelMCD diffuse large B-cell lymphoma
Doid DescriptionA diffuse large B-cell lymphoma that is categorized as MCD with high probability by the LymphGen algorithm. This is based on a combination of genetic features and MCD DLBCLs often, but do not always, have the most common hot spot mutation in MYD88 (L265P) and/or activating mutations in CD79B. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting PIM1 and/or ETV6, which can be coding or non-coding.
Disease Node Iddisease_node_15574
Doid IdDOID_0081066
LabelMcd Diffuse Large B-Cell Lymphoma