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St2 Diffuse Large B-Cell Lymphoma

Disease ID: disease_node_15572

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SubclassofDOID_0050745
Data SourceDOID
SynonymsST2 DLBCL
Doid LabelST2 diffuse large B-cell lymphoma
Doid DescriptionA diffuse large B-cell lymphoma that is categorized as ST2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and ST2 DLBCLs often, but do not always, have missense or nonsense mutations affecting TET2 and NFKBIA. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting some combination of SGK1, ZFP36L1, SOCS1, HIST1H1E and CD83, which can be coding or non-coding.
Disease Node Iddisease_node_15572
Doid IdDOID_0081068
LabelSt2 Diffuse Large B-Cell Lymphoma