Sickle Cell Disease
Disease ID: disease_node_15319
Connections displayed (default: 10).
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| Dbxref | MIM:603903 |
|---|---|
| Subclassof | DOID_620 |
| Data Source | DOID |
| Doid Label | sickle cell disease |
| Doid Description | A blood protein disease that is characterized by chronic hemolytic anemia and intermittent vaso-occlusive events that result in tissue ischemia leading to acute and chronic pain as well as organ damage that can affect any organ system, resulting from the replacement of one of the beta-globin subunits in hemoglobin with atypical hemoglobin molecules called hemoglobin S which can distort red blood cells into a sickle or crescent shape. Sickle cell disease subtypes should include a detailed genotypic description for the hemoglobin molecules (e.g., Hb S/S, Hb S/C, Hb S/β0-thalassemia). |
| Disease Node Id | disease_node_15319 |
| Doid Id | DOID_0081445 |
| Label | Sickle Cell Disease |
- Outgoing r'ship
SUBCLASS_OFto/from Blood Protein Disorders(ID:disease_node_1623) (Disease) - Incoming r'ship
SUBCLASS_OFto/from Hemoglobin Sc Disease(ID:disease_node_3807) (Disease) - Incoming r'ship
SUBCLASS_OFto/from Anemia, Sickle Cell(ID:disease_node_1204) (Disease)