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Amyotrophic Lateral Sclerosis Type 25

Disease ID: disease_node_14040

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DbxrefMIM:617921
SubclassofDOID_0050736, DOID_332
Data SourceDOID
Doid Labelamyotrophic lateral sclerosis type 25
Doid DescriptionAn amyotrophic lateral sclerosis that is characterized by rapidly progressive muscle weakness and death due to respiratory failure and that has_material_basis_in heterozygous mutation in the KIF5A gene on chromosome 12q13. ALS25 may have a lower median age at onset (46.5 years) and longer median survival (10 years) than that found in epidemiologic studies (62.5 years and 20 to 30 months, respectively).
Has Material Basis InGENO_0000147
Disease Node Iddisease_node_14040
Doid IdDOID_0081379
LabelAmyotrophic Lateral Sclerosis Type 25