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Juvenile Amyotrophic Lateral Sclerosis Type 27

Disease ID: disease_node_14038

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DbxrefMIM:620285
SubclassofDOID_0050736, DOID_332
Data SourceDOID
Doid Labeljuvenile amyotrophic lateral sclerosis type 27
Doid DescriptionAn amyotrophic lateral sclerosis that is characterized by early childhood-onset lower extremity spasticity manifesting as toe walking and gait abnormalities, followed by progressive lower motor neuron-mediated weakness without sensory signs or symptoms and that has_material_basis_in heterozygous mutation in the SPTLC1 gene on chromosome 9q22.
Existence Starts DuringHP_0003621
Has Material Basis InGENO_0000147
Disease Node Iddisease_node_14038
Doid IdDOID_0081381
LabelJuvenile Amyotrophic Lateral Sclerosis Type 27