Cd3Gamma Deficiency
Disease ID: disease_node_13323
Connections displayed (default: 10).
Loading graph...
| Subclassof | DOID_0050737, DOID_627 |
|---|---|
| Data Source | DOID |
| Doid Label | CD3gamma deficiency |
| Doid Description | A severe combined immunodeficiency that has_material_basis_in autosomal recessive mutations in the gene coding for T-cell surface glycoprotein CD3gamma chain precursors. Patients with CD3gamma deficiency have a severe defect in the expression of the T-cell receptor CD3-complex. Affected patients have decreased T-cell numbers and function, B cells are variably affected. |
| Has Material Basis In | GENO_0000148 |
| Disease Node Id | disease_node_13323 |
| Doid Id | DOID_0060018 |
| Label | Cd3Gamma Deficiency |
- Outgoing r'ship
SUBCLASS_OFto/from Autosomal Recessive Disease(ID:disease_node_13241) (Disease)