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Immunodeficiency 15B

Disease ID: disease_node_13318

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DbxrefMIM:615592, UMLS_CUI:C4747743
SubclassofDOID_0050737, DOID_627
Data SourceDOID
SynonymsIMD15B
Doid Labelimmunodeficiency 15B
Doid DescriptionA severe combined immunodeficiency characterized by onset in infancy of life-threatening bacterial, fungal, and viral infections, failure to thrive, impaired differentiation and activation of immune cells, and hypo- or agammaglobulinemia but relatively normal B and T cell numbers that has_material_basis_in homozygous or compound heterozygous mutation in the IKBKB gene on chromosome 8p11.21.
Has Material Basis InGENO_0000148
Disease Node Iddisease_node_13318
Doid IdDOID_0111959
LabelImmunodeficiency 15B