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Immunodeficiency 60

Disease ID: disease_node_13299

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DbxrefMIM:618394, UMLS_CUI:C5193072
SubclassofDOID_0050736, DOID_628
Data SourceDOID
SynonymsBACH2-related immunodeficiency and autoimmunity, BRIDA, IMD60
Doid Labelimmunodeficiency 60
Doid DescriptionA combined T cell and B cell immunodeficiency characterized by variably decreased immunoglobulin production, decreased T-regulatory cells, overall impaired lymphocyte maturation, inflammatory bowel disease and recurrent sinopulmonary infections that has_material_basis_in heterozygous mutation in the BACH2 gene on chromosome 6q15.
Has Material Basis InGENO_0000147
Disease Node Iddisease_node_13299
Doid IdDOID_0111954
LabelImmunodeficiency 60