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Multiple Acyl Coenzyme A Dehydrogenase Deficiency

Disease ID: disease_node_11825

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DbxrefICD10CM:E71.313, MESH:D054069, MIM:231680, NCI:C84907, ORDO:26791, SNOMEDCT_US_2023_03_01:22886006, UMLS_CUI:C0268596, UMLS_CUI:C1856401, UMLS_CUI:C1856403, UMLS_CUI:C1856405
SubclassofDOID_655
Data SourceDOID, MESH
SynonymsMAD deficiency, MADD, electron transfer flavoprotein deficiency, electron transfer flavoprotein ubiquinone oxidoreductase deficiency, glutaric acidemia type 2, glutaric aciduria type 2
Mesh IdD054069
Mesh LabelMultiple Acyl Coenzyme A Dehydrogenase Deficiency
Mesh SubclassofD028361, D000592
Doid Labelmultiple acyl-CoA dehydrogenase deficiency
Doid DescriptionAn inherited metabolic disorder characterized by the body's inability to break down proteins and fats to produce energy. It is a disorder of fatty acid, amino acid, and choline metabolism and has an autosomal recessive inheritance pattern. It has_material_basis_in mutations in the ETFA, ETFB and ETFDH genes. It presents three clinical phenotypes: a neonatal-onset form with congenital anomalies (type I), a neonatal-onset form without congenital anomalies (type II), and a late-onset form (type III). The neonatal-onset forms are usually fatal.
Has PhenotypeHP_0032245
Disease Node Iddisease_node_11825
Doid IdDOID_0060358
Disease Has Basis InSO_0001537
LabelMultiple Acyl Coenzyme A Dehydrogenase Deficiency