Lymphohistiocytosis, Hemophagocytic
Disease ID: disease_node_11475
Connections displayed (default: 10).
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| Dbxref | GARD:6589, ICD10CM:D76.1, MESH:D051359, MIM:PS267700, NCI:C34792, ORDO:540, SNOMEDCT_US_2023_03_01:190958003, UMLS_CUI:C0024291 |
|---|---|
| Subclassof | DOID_75 |
| Data Source | DOID, MESH |
| Synonyms | haemophagocytic syndrome |
| Mesh Id | D051359 |
| Mesh Label | Lymphohistiocytosis, Hemophagocytic |
| Mesh Subclassof | D015616 |
| Doid Label | hemophagocytic lymphohistiocytosis |
| Doid Description | A lymphatic system disease that is characterized by an expansion of the monocyte-macrophage population and intense hemophagocytosis. It can occur de novo, but more often occurs in the setting of another disorder, usually an infection or a maligcy. A clinical picture of fever, hepatosplenomegaly, lymphadenopathy and peripheral pancytopenia. The morphologic hallmark of this syndrome is the phagocytosis of hematopoietic elements by morphologically normal macrophages. Xref MGI. MESH:C537250 added from NeuroDevNet [WAK]. |
| Has Symptom | SYMP_0000521, SYMP_0019142, SYMP_0000047 |
| Disease Node Id | disease_node_11475 |
| Doid Id | DOID_0050120 |
| Label | Lymphohistiocytosis, Hemophagocytic |
| Doid Alternate Ids | DOID_6453 |
- Outgoing r'ship
HAS_SYMPTOMto/from Enlargement Of Lymph Nodes(ID:disease_node_20946) (Disease) - Outgoing r'ship
HAS_SYMPTOMto/from Lymphadenopathy(ID:disease_node_216;disease_node_20947) (Disease) - Outgoing r'ship
HAS_SYMPTOMto/from Hepatosplenomegaly(ID:disease_node_20956) (Disease) - Outgoing r'ship
SUBCLASS_OFto/from Lymphatic Diseases(ID:disease_node_4897) (Disease) - Incoming r'ship
SUBCLASS_OFto/from Familial Hemophagocytic Lymphohistiocytosis 5(ID:disease_node_18243) (Disease) - Incoming r'ship
SUBCLASS_OFto/from Familial Hemophagocytic Lymphohistiocytosis 1(ID:disease_node_18247) (Disease) - Incoming r'ship
SUBCLASS_OFto/from Familial Hemophagocytic Lymphohistiocytosis 3(ID:disease_node_18245) (Disease) - Incoming r'ship
SUBCLASS_OFto/from Familial Hemophagocytic Lymphohistiocytosis 4(ID:disease_node_18244) (Disease) - Incoming r'ship
SUBCLASS_OFto/from Familial Hemophagocytic Lymphohistiocytosis 2(ID:disease_node_18246) (Disease)