Superfamily code
|    | No of members
|    |    | Superfamily name
|
| 100879 |    | 5 |    |    | Lesion bypass DNA polymerase (Y-family), little finger domain |
| 100895 |    | 3 |    |    | Kazal-type serine protease inhibitors |
| 100897 |    | 2 |    |    | Plant proteinase inhibitors |
| 100934 |    | 2 |    |    | Heat shock protein 70kD (HSP70), C-terminal subdomain |
| 100939 |    | 3 |    |    | SPOC domain-like |
| 100950 |    | 20 |    |    | NagB/RpiA/CoA transferase-like |
| 101089 |    | 2 |    |    | Phosphoprotein XD domain |
| 101094 |    | 2 |    |    | Staphylocoagulase |
| 101116 |    | 2 |    |    | Flagellar export chaperone FliS |
| 101148 |    | 2 |    |    | Plant invertase/pectin methylesterase inhibitor |
| 101215 |    | 2 |    |    | KaiA/RbsU domain |
| 101238 |    | 2 |    |    | XPC-binding domain |
| 101257 |    | 2 |    |    | Flavivirus capsid protein C |
| 101288 |    | 6 |    |    | L27 domain |
| 101386 |    | 8 |    |    | all-alpha NTP pyrophosphatases |
| 101447 |    | 2 |    |    | Formin homology 2 domain (FH2 domain) |
| 101690 |    | 2 |    |    | PAZ domain |
| 101744 |    | 3 |    |    | Rof/RNase P subunit-like |
| 101790 |    | 5 |    |    | Aminomethyltransferase beta-barrel domain |
| 101801 |    | 2 |    |    | Surface presentation of antigens (SPOA) |
| 101821 |    | 6 |    |    | Aminopeptidase/glucanase lid domain |
| 101874 |    | 2 |    |    | YceI-like |
| 101898 |    | 2 |    |    | NHL repeat |
| 101904 |    | 2 |    |    | GyrA/ParC C-terminal domain-like |
| 101912 |    | 3 |    |    | Sema domain |
| 101936 |    | 3 |    |    | DNA-binding pseudobarrel domain |
| 102114 |    | 2 |    |    | Radical SAM enzymes |
| 102198 |    | 2 |    |    | Putative cyclase |
| 102405 |    | 5 |    |    | MoCo carrier protein-like |
| 102462 |    | 2 |    |    | Peptidyl-tRNA hydrolase II |
| 102588 |    | 2 |    |    | LmbE-like |
| 102645 |    | 2 |    |    | CoaB-like |
| 102705 |    | 3 |    |    | NIF3 (NGG1p interacting factor 3)-like |
| 102824 |    | 2 |    |    | Colicin D/E5 nuclease domain |
| 102886 |    | 2 |    |    | Coproporphyrinogen III oxidase |
| 103025 |    | 4 |    |    | Folate-binding domain |
| 103039 |    | 2 |    |    | CheC-like |
| 103068 |    | 3 |    |    | Nucleocapsid protein dimerization domain |
| 103088 |    | 2 |    |    | OmpA-like |
| 103190 |    | 3 |    |    | Sensory domain-like |
| 103196 |    | 4 |    |    | Roadblock/LC7 domain |
| 103247 |    | 2 |    |    | TT1751-like |
| 103263 |    | 3 |    |    | Chorismate synthase, AroC |
| 103436 |    | 2 |    |    | PetL subunit of the cytochrome b6f complex |
| 103441 |    | 2 |    |    | PetM subunit of the cytochrome b6f complex |
| 103473 |    | 2 |    |    | MFS general substrate transporter |
| 103575 |    | 3 |    |    | Plexin repeat |
| 103657 |    | 3 |    |    | BAR/IMD domain-like |
| 109604 |    | 5 |    |    | HD-domain/PDEase-like |
| 109709 |    | 2 |    |    | KorB DNA-binding domain-like |
| 109755 |    | 4 |    |    | PhoU-like |
| 109797 |    | 2 |    |    | Bacteriocin immunity protein-like |
| 109854 |    | 2 |    |    | DinB/YfiT-like putative metalloenzymes |
| 109885 |    | 3 |    |    | I/LWEQ domain |
| 109998 |    | 2 |    |    | Triger factor/SurA peptide-binding domain-like |
| 110069 |    | 2 |    |    | ApaG-like |
| 110296 |    | 2 |    |    | Oligoxyloglucan reducing end-specific cellobiohydrolase |
| 110304 |    | 2 |    |    | Coronavirus RNA-binding domain |
| 110455 |    | 2 |    |    | Toprim domain |
| 110849 |    | 2 |    |    | ParB/Sulfiredoxin |
| 110857 |    | 3 |    |    | BtrG-like |
| 110993 |    | 2 |    |    | eIF-2-alpha, C-terminal domain |
| 111038 |    | 3 |    |    | YjbQ-like |
| 111126 |    | 2 |    |    | Ligand-binding domain in the NO signalling and Golgi transport |
| 111283 |    | 2 |    |    | Putative modulator of DNA gyrase, PmbA/TldD |
| 111321 |    | 3 |    |    | AF1104-like |
| 111331 |    | 2 |    |    | NAD kinase |
| 116726 |    | 2 |    |    | TrkA C-terminal domain-like |
| 116734 |    | 5 |    |    | DNA methylase specificity domain |
| 116742 |    | 3 |    |    | eIF2alpha middle domain-like |
| 116846 |    | 2 |    |    | MIT domain |
| 116927 |    | 2 |    |    | EspA/CesA-like |
| 117289 |    | 2 |    |    | Nucleoporin domain |
| 117396 |    | 2 |    |    | TM1631-like |
| 117856 |    | 2 |    |    | AF0104/ALDC/Ptd012-like |
| 117916 |    | 4 |    |    | Fe-S cluster assembly (FSCA) domain-like |
| 117987 |    | 2 |    |    | CRISPR-associated protein |
| 118310 |    | 2 |    |    | AN1-like Zinc finger |
| 118352 |    | 2 |    |    | HSP33 redox switch-like |
| 140111 |    | 3 |    |    | Endosomal sorting complex assembly domain |
| 140125 |    | 2 |    |    | Rabenosyn-5 Rab-binding domain-like |
| 140356 |    | 2 |    |    | PPK N-terminal domain-like |
| 140383 |    | 2 |    |    | BSD domain-like |
| 140415 |    | 3 |    |    | YppE-like |
| 140453 |    | 2 |    |    | EsxAB dimer-like |
| 140459 |    | 2 |    |    | PE/PPE dimer-like |
| 140591 |    | 2 |    |    | Type III secretion system domain |
| 140657 |    | 2 |    |    | Hyaluronidase post-catalytic domain-like |
| 140663 |    | 2 |    |    | TTHA0068-like |
| 140693 |    | 2 |    |    | IpaD-like |
| 140718 |    | 2 |    |    | Mediator hinge subcomplex-like |
| 140809 |    | 2 |    |    | Rhabdovirus nucleoprotein-like |
| 140924 |    | 3 |    |    | Duffy binding domain-like |
| 140959 |    | 3 |    |    | Indolic compounds 2,3-dioxygenase-like |
| 140984 |    | 3 |    |    | PTPA-like |
| 141066 |    | 2 |    |    | ICP-like |
| 141072 |    | 2 |    |    | CalX-like |
| 141371 |    | 3 |    |    | PilZ domain-like |
| 141480 |    | 3 |    |    | Extracellular hemoglobin linker subunit, receptor domain |
| 141523 |    | 2 |    |    | L,D-transpeptidase catalytic domain-like |
| 141571 |    | 3 |    |    | Pentapeptide repeat-like |
| 141658 |    | 2 |    |    | Bacteriophage trimeric proteins domain |
| 141739 |    | 3 |    |    | MFPT repeat-like |
| 142338 |    | 2 |    |    | CofD-like |
| 142535 |    | 2 |    |    | AF0625-like |
| 142877 |    | 2 |    |    | EndoU-like |
| 142906 |    | 2 |    |    | YjbR-like |
| 142913 |    | 2 |    |    | YktB/PF0168-like |
| 143011 |    | 3 |    |    | RelE-like |
| 143026 |    | 2 |    |    | Kinetochore globular domain |
| 143081 |    | 4 |    |    | BB1717-like |
| 143120 |    | 2 |    |    | YefM-like |
| 143414 |    | 2 |    |    | CcmK-like |
| 143422 |    | 2 |    |    | Transposase IS200-like |
| 143437 |    | 3 |    |    | THUMP domain-like |
| 143456 |    | 3 |    |    | VC0467-like |
| 143548 |    | 2 |    |    | Serine metabolism enzymes domain |
| 143560 |    | 2 |    |    | MK0786-like |
| 143602 |    | 2 |    |    | STIV B116-like |
| 143724 |    | 2 |    |    | PHP14-like |
| 143749 |    | 2 |    |    | Phage tail protein-like |
| 143800 |    | 2 |    |    | L28p-like |
| 143847 |    | 3 |    |    | XisI-like |
| 144052 |    | 2 |    |    | Thermophilic metalloprotease-like |
| 144064 |    | 2 |    |    | Heme iron utilization protein-like |
| 144074 |    | 2 |    |    | E2F-DP heterodimerization region |
| 144091 |    | 2 |    |    | Rhomboid-like |
| 144122 |    | 2 |    |    | Tim10-like |
| 144210 |    | 2 |    |    | Nop10-like SnoRNP |
| 144217 |    | 2 |    |    | CSL zinc finger |
| 144232 |    | 3 |    |    | HIT/MYND zinc finger-like |
| 46458 |    | 37 |    |    | Globin-like |
| 46548 |    | 3 |    |    | alpha-helical ferredoxin |
| 46557 |    | 2 |    |    | GreA transcript cleavage protein, N-terminal domain |
| 46561 |    | 3 |    |    | Ribosomal protein L29 (L29p) |
| 46565 |    | 6 |    |    | Chaperone J-domain |
| 46579 |    | 2 |    |    | Prefoldin |
| 46585 |    | 2 |    |    | HR1 repeat |
| 46589 |    | 4 |    |    | tRNA-binding arm |
| 46604 |    | 2 |    |    | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| 46609 |    | 4 |    |    | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| 46689 |    | 48 |    |    | Homeodomain-like |
| 46767 |    | 2 |    |    | Methylated DNA-protein cysteine methyltransferase, C-terminal domain |
| 46774 |    | 4 |    |    | ARID-like |
| 46785 |    | 47 |    |    | "Winged helix" DNA-binding domain |
| 46894 |    | 12 |    |    | C-terminal effector domain of the bipartite response regulators |
| 46906 |    | 2 |    |    | Ribosomal protein L11, C-terminal domain |
| 46915 |    | 2 |    |    | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| 46929 |    | 3 |    |    | DNA helicase RuvA subunit, C-terminal domain |
| 46934 |    | 28 |    |    | UBA-like |
| 46938 |    | 3 |    |    | CRAL/TRIO N-terminal domain |
| 46946 |    | 5 |    |    | S13-like H2TH domain |
| 46950 |    | 2 |    |    | Double-stranded DNA-binding domain |
| 46955 |    | 9 |    |    | Putative DNA-binding domain |
| 46966 |    | 10 |    |    | Spectrin repeat |
| 46977 |    | 5 |    |    | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| 46988 |    | 2 |    |    | Tubulin chaperone cofactor A |
| 46997 |    | 4 |    |    | Bacterial immunoglobulin/albumin-binding domains |
| 47005 |    | 2 |    |    | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex |
| 47014 |    | 3 |    |    | Protozoan pheromone proteins |
| 47027 |    | 2 |    |    | Acyl-CoA binding protein |
| 47031 |    | 4 |    |    | Second domain of FERM |
| 47045 |    | 2 |    |    | RAP domain-like |
| 47050 |    | 2 |    |    | VHP, Villin headpiece domain |
| 47060 |    | 4 |    |    | S15/NS1 RNA-binding domain |
| 47072 |    | 2 |    |    | Cysteine alpha-hairpin motif |
| 47082 |    | 2 |    |    | Fertilization protein |
| 47090 |    | 4 |    |    | PGBD-like |
| 47095 |    | 9 |    |    | HMG-box |
| 47113 |    | 21 |    |    | Histone-fold |
| 47175 |    | 7 |    |    | Cytochromes |
| 47195 |    | 2 |    |    | TMV-like viral coat proteins |
| 47203 |    | 9 |    |    | Acyl-CoA dehydrogenase C-terminal domain-like |
| 47220 |    | 10 |    |    | alpha-catenin/vinculin-like |
| 47226 |    | 7 |    |    | Histidine-containing phosphotransfer domain, HPT domain |
| 47233 |    | 3 |    |    | Bacterial GAP domain |
| 47240 |    | 11 |    |    | Ferritin-like |
| 47323 |    | 9 |    |    | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| 47336 |    | 7 |    |    | ACP-like |
| 47353 |    | 3 |    |    | Retrovirus capsid dimerization domain-like |
| 47364 |    | 4 |    |    | Domain of the SRP/SRP receptor G-proteins |
| 47370 |    | 5 |    |    | Bromodomain |
| 47384 |    | 3 |    |    | Homodimeric domain of signal transducing histidine kinase |
| 47391 |    | 2 |    |    | Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit |
| 47396 |    | 3 |    |    | Transcription factor IIA (TFIIA), alpha-helical domain |
| 47406 |    | 2 |    |    | SinR repressor dimerisation domain-like |
| 47413 |    | 24 |    |    | lambda repressor-like DNA-binding domains |
| 47446 |    | 2 |    |    | Signal peptide-binding domain |
| 47454 |    | 2 |    |    | A DNA-binding domain in eukaryotic transcription factors |
| 47459 |    | 7 |    |    | HLH, helix-loop-helix DNA-binding domain |
| 47565 |    | 5 |    |    | Insect pheromone/odorant-binding proteins |
| 47571 |    | 2 |    |    | Cloroperoxidase |
| 47576 |    | 10 |    |    | Calponin-homology domain, CH-domain |
| 47587 |    | 2 |    |    | Domain of poly(ADP-ribose) polymerase |
| 47592 |    | 3 |    |    | SWIB/MDM2 domain |
| 47598 |    | 12 |    |    | Ribbon-helix-helix |
| 47616 |    | 28 |    |    | Glutathione S-transferase (GST), C-terminal domain |
| 47648 |    | 4 |    |    | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| 47655 |    | 2 |    |    | STAT |
| 47661 |    | 5 |    |    | t-snare proteins |
| 47672 |    | 2 |    |    | Transferrin receptor-like dimerisation domain |
| 47676 |    | 2 |    |    | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| 47699 |    | 8 |    |    | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| 47729 |    | 5 |    |    | IHF-like DNA-binding proteins |
| 47741 |    | 3 |    |    | CO dehydrogenase ISP C-domain like |
| 47769 |    | 17 |    |    | SAM/Pointed domain |
| 47781 |    | 11 |    |    | RuvA domain 2-like |
| 47789 |    | 3 |    |    | C-terminal domain of RNA polymerase alpha subunit |
| 47794 |    | 4 |    |    | Rad51 N-terminal domain-like |
| 47802 |    | 3 |    |    | DNA polymerase beta, N-terminal domain-like |
| 47807 |    | 3 |    |    | 5' to 3' exonuclease, C-terminal subdomain |
| 47819 |    | 10 |    |    | HRDC-like |
| 47823 |    | 2 |    |    | lambda integrase-like, N-terminal domain |
| 47836 |    | 6 |    |    | Retroviral matrix proteins |
| 47857 |    | 2 |    |    | Apolipophorin-III |
| 47862 |    | 5 |    |    | Saposin |
| 47874 |    | 3 |    |    | Annexin |
| 47895 |    | 3 |    |    | Transducin (alpha subunit), insertion domain |
| 47917 |    | 2 |    |    | C-terminal domain of alpha and beta subunits of F1 ATP synthase |
| 47923 |    | 2 |    |    | Ypt/Rab-GAP domain of gyp1p |
| 47933 |    | 2 |    |    | ERP29 C domain-like |
| 47943 |    | 5 |    |    | Retrovirus capsid protein, N-terminal core domain |
| 47954 |    | 9 |    |    | Cyclin-like |
| 47973 |    | 2 |    |    | Ribosomal protein S7 |
| 47979 |    | 2 |    |    | Iron-dependent repressor protein, dimerization domain |
| 47986 |    | 13 |    |    | DEATH domain |
| 48013 |    | 5 |    |    | NusB-like |
| 48019 |    | 10 |    |    | DNA polymerase III clamp loader subunits, C-terminal domain |
| 48034 |    | 2 |    |    | Guanido kinase N-terminal domain |
| 48050 |    | 2 |    |    | Hemocyanin, N-terminal domain |
| 48056 |    | 2 |    |    | Di-copper centre-containing domain |
| 48065 |    | 7 |    |    | DBL homology domain (DH-domain) |
| 48081 |    | 2 |    |    | Methyl-coenzyme M reductase alpha and beta chain C-terminal domain |
| 48097 |    | 6 |    |    | Regulator of G-protein signaling, RGS |
| 48113 |    | 6 |    |    | Heme-dependent peroxidases |
| 48150 |    | 10 |    |    | DNA-glycosylase |
| 48163 |    | 2 |    |    | An anticodon-binding domain of class I aminoacyl-tRNA synthetases |
| 48168 |    | 2 |    |    | R1 subunit of ribonucleotide reductase, N-terminal domain |
| 48173 |    | 4 |    |    | Cryptochrome/photolyase FAD-binding domain |
| 48179 |    | 10 |    |    | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| 48201 |    | 3 |    |    | Uteroglobin-like |
| 48208 |    | 12 |    |    | Six-hairpin glycosidases |
| 48225 |    | 4 |    |    | Seven-hairpin glycosidases |
| 48230 |    | 6 |    |    | Chondroitin AC/alginate lyase |
| 48239 |    | 7 |    |    | Terpenoid cyclases/Protein prenyltransferases |
| 48256 |    | 3 |    |    | Citrate synthase |
| 48264 |    | 16 |    |    | Cytochrome P450 |
| 48295 |    | 2 |    |    | TrpR-like |
| 48300 |    | 2 |    |    | Ribosomal protein L7/12, oligomerisation (N-terminal) domain |
| 48310 |    | 2 |    |    | Aldehyde ferredoxin oxidoreductase, C-terminal domains |
| 48317 |    | 3 |    |    | Acid phosphatase/Vanadium-dependent haloperoxidase |
| 48334 |    | 2 |    |    | DNA repair protein MutS, domain III |
| 48345 |    | 3 |    |    | A virus capsid protein alpha-helical domain |
| 48350 |    | 4 |    |    | GTPase activation domain, GAP |
| 48403 |    | 14 |    |    | Ankyrin repeat |
| 48425 |    | 3 |    |    | Sec7 domain |
| 48439 |    | 2 |    |    | Protein prenylyltransferase |
| 48452 |    | 15 |    |    | TPR-like |
| 48464 |    | 6 |    |    | ENTH/VHS domain |
| 48484 |    | 2 |    |    | Lipoxigenase |
| 48498 |    | 22 |    |    | Tetracyclin repressor-like, C-terminal domain |
| 48508 |    | 17 |    |    | Nuclear receptor ligand-binding domain |
| 48537 |    | 3 |    |    | Phospholipase C/P1 nuclease |
| 48552 |    | 5 |    |    | Serum albumin-like |
| 48557 |    | 8 |    |    | L-aspartase-like |
| 48576 |    | 8 |    |    | Terpenoid synthases |
| 48592 |    | 2 |    |    | GroEL equatorial domain-like |
| 48600 |    | 7 |    |    | Chorismate mutase II |
| 48613 |    | 13 |    |    | Heme oxygenase-like |
| 48619 |    | 3 |    |    | Phospholipase A2, PLA2 |
| 48670 |    | 2 |    |    | Transducin (heterotrimeric G protein), gamma chain |
| 48695 |    | 6 |    |    | Multiheme cytochromes |
| 49265 |    | 47 |    |    | Fibronectin type III |
| 49299 |    | 3 |    |    | PKD domain |
| 49303 |    | 5 |    |    | beta-Galactosidase/glucuronidase domain |
| 49309 |    | 8 |    |    | Transglutaminase, two C-terminal domains |
| 49313 |    | 7 |    |    | Cadherin-like |
| 49319 |    | 2 |    |    | Actinoxanthin-like |
| 49329 |    | 4 |    |    | Cu,Zn superoxide dismutase-like |
| 49344 |    | 2 |    |    | CBD9-like |
| 49348 |    | 5 |    |    | Clathrin adaptor appendage domain |
| 49354 |    | 6 |    |    | PapD-like |
| 49367 |    | 2 |    |    | Superoxide reductase-like |
| 49373 |    | 6 |    |    | Invasin/intimin cell-adhesion fragments |
| 49384 |    | 8 |    |    | Carbohydrate-binding domain |
| 49401 |    | 10 |    |    | Bacterial adhesins |
| 49417 |    | 8 |    |    | p53-like transcription factors |
| 49452 |    | 4 |    |    | Starch-binding domain-like |
| 49464 |    | 3 |    |    | Carboxypeptidase regulatory domain-like |
| 49478 |    | 3 |    |    | Cna protein B-type domain |
| 49482 |    | 4 |    |    | Aromatic compound dioxygenase |
| 49493 |    | 4 |    |    | HSP40/DnaJ peptide-binding domain |
| 49584 |    | 3 |    |    | Periplasmic chaperone C-domain |
| 49599 |    | 4 |    |    | TRAF domain-like |
| 49695 |    | 12 |    |    | gamma-Crystallin-like |
| 49723 |    | 4 |    |    | Lipase/lipooxygenase domain (PLAT/LH2 domain) |
| 49742 |    | 4 |    |    | PHM/PNGase F |
| 49749 |    | 5 |    |    | Group II dsDNA viruses VP |
| 49764 |    | 8 |    |    | HSP20-like chaperones |
| 49777 |    | 3 |    |    | PEBP-like |
| 49785 |    | 21 |    |    | Galactose-binding domain-like |
| 49818 |    | 7 |    |    | Viral protein domain |
| 49835 |    | 5 |    |    | Virus attachment protein globular domain |
| 49842 |    | 13 |    |    | TNF-like |
| 49854 |    | 5 |    |    | Spermadhesin, CUB domain |
| 49863 |    | 6 |    |    | Hyaluronate lyase-like, C-terminal domain |
| 49879 |    | 15 |    |    | SMAD/FHA domain |
| 49899 |    | 17 |    |    | Concanavalin A-like lectins/glucanases |
| 49998 |    | 5 |    |    | Amine oxidase catalytic domain |
| 50012 |    | 2 |    |    | EV matrix protein |
| 50022 |    | 12 |    |    | ISP domain |
| 50037 |    | 5 |    |    | C-terminal domain of transcriptional repressors |
| 50044 |    | 32 |    |    | SH3-domain |
| 50084 |    | 4 |    |    | Myosin S1 fragment, N-terminal domain |
| 50090 |    | 5 |    |    | Electron transport accessory proteins |
| 50104 |    | 11 |    |    | Translation proteins SH3-like domain |
| 50118 |    | 4 |    |    | Cell growth inhibitor/plasmid maintenance toxic component |
| 50122 |    | 2 |    |    | DNA-binding domain of retroviral integrase |
| 50129 |    | 19 |    |    | GroES-like |
| 50156 |    | 50 |    |    | PDZ domain-like |
| 50176 |    | 2 |    |    | N-terminal domains of the minor coat protein g3p |
| 50182 |    | 14 |    |    | Sm-like ribonucleoproteins |
| 50193 |    | 2 |    |    | Ribosomal protein L14 |
| 50203 |    | 10 |    |    | Bacterial enterotoxins |
| 50242 |    | 5 |    |    | TIMP-like |
| 50324 |    | 2 |    |    | Inorganic pyrophosphatase |
| 50331 |    | 11 |    |    | MOP-like |
| 50341 |    | 2 |    |    | CheW-like |
| 50346 |    | 4 |    |    | PRC-barrel domain |
| 50382 |    | 2 |    |    | Agglutinin |
| 50386 |    | 8 |    |    | STI-like |
| 50405 |    | 5 |    |    | Actin-crosslinking proteins |
| 50443 |    | 2 |    |    | FucI/AraA C-terminal domain-like |
| 50447 |    | 17 |    |    | Translation proteins |
| 50465 |    | 6 |    |    | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain |
| 50475 |    | 22 |    |    | FMN-binding split barrel |
| 50486 |    | 5 |    |    | FMT C-terminal domain-like |
| 50494 |    | 35 |    |    | Trypsin-like serine proteases |
| 50615 |    | 2 |    |    | N-terminal domain of alpha and beta subunits of F1 ATP synthase |
| 50621 |    | 7 |    |    | Alanine racemase C-terminal domain-like |
| 50630 |    | 13 |    |    | Acid proteases |
| 50677 |    | 4 |    |    | ValRS/IleRS/LeuRS editing domain |
| 50685 |    | 3 |    |    | Barwin-like endoglucanases |
| 50692 |    | 14 |    |    | ADC-like |
| 50715 |    | 2 |    |    | Ribosomal protein L25-like |
| 50729 |    | 46 |    |    | PH domain-like |
| 50784 |    | 3 |    |    | Transcription factor IIA (TFIIA), beta-barrel domain |
| 50789 |    | 3 |    |    | Herpes virus serine proteinase, assemblin |
| 50800 |    | 5 |    |    | PK beta-barrel domain-like |
| 50814 |    | 25 |    |    | Lipocalins |
| 50876 |    | 2 |    |    | Avidin/streptavidin |
| 50882 |    | 4 |    |    | beta-Barrel protease inhibitors |
| 50886 |    | 2 |    |    | D-aminopeptidase, middle and C-terminal domains |
| 50891 |    | 5 |    |    | Cyclophilin-like |
| 50904 |    | 2 |    |    | Oncogene products |
| 50911 |    | 5 |    |    | Mannose 6-phosphate receptor domain |
| 50916 |    | 2 |    |    | Rap30/74 interaction domains |
| 50923 |    | 5 |    |    | Hemopexin-like domain |
| 50939 |    | 9 |    |    | Sialidases |
| 50969 |    | 5 |    |    | YVTN repeat-like/Quinoprotein amine dehydrogenase |
| 50978 |    | 12 |    |    | WD40 repeat-like |
| 50985 |    | 2 |    |    | RCC1/BLIP-II |
| 50993 |    | 2 |    |    | Peptidase/esterase 'gauge' domain |
| 50998 |    | 3 |    |    | Quinoprotein alcohol dehydrogenase-like |
| 51011 |    | 22 |    |    | Glycosyl hydrolase domain |
| 51045 |    | 8 |    |    | WW domain |
| 51055 |    | 3 |    |    | Carbohydrate binding domain |
| 51069 |    | 4 |    |    | Carbonic anhydrase |
| 51087 |    | 2 |    |    | Outer surface protein |
| 51096 |    | 3 |    |    | delta-Endotoxin (insectocide), middle domain |
| 51101 |    | 3 |    |    | Mannose-binding lectins |
| 51110 |    | 2 |    |    | alpha-D-mannose-specific plant lectins |
| 51126 |    | 9 |    |    | Pectin lyase-like |
| 51161 |    | 7 |    |    | Trimeric LpxA-like enzymes |
| 51182 |    | 7 |    |    | RmlC-like cupins |
| 51197 |    | 5 |    |    | Clavaminate synthase-like |
| 51206 |    | 15 |    |    | cAMP-binding domain-like |
| 51219 |    | 2 |    |    | TRAP-like |
| 51225 |    | 2 |    |    | Fibre shaft of virus attachment proteins |
| 51230 |    | 7 |    |    | Single hybrid motif |
| 51246 |    | 6 |    |    | Rudiment single hybrid motif |
| 51261 |    | 2 |    |    | Duplicated hybrid motif |
| 51269 |    | 3 |    |    | AFP III-like domain |
| 51283 |    | 9 |    |    | dUTPase-like |
| 51294 |    | 5 |    |    | Hedgehog/intein (Hint) domain |
| 51306 |    | 3 |    |    | LexA/Signal peptidase |
| 51332 |    | 2 |    |    | E2 regulatory, transactivation domain |
| 51338 |    | 14 |    |    | Composite domain of metallo-dependent hydrolases |
| 51344 |    | 2 |    |    | Epsilon subunit of F1F0-ATP synthase N-terminal domain |
| 51351 |    | 3 |    |    | Triosephosphate isomerase (TIM) |
| 51366 |    | 22 |    |    | Ribulose-phoshate binding barrel |
| 51391 |    | 2 |    |    | Thiamin phosphate synthase |
| 51395 |    | 17 |    |    | FMN-linked oxidoreductases |
| 51412 |    | 3 |    |    | Inosine monophosphate dehydrogenase (IMPDH) |
| 51419 |    | 8 |    |    | PLP-binding barrel |
| 51430 |    | 8 |    |    | NAD(P)-linked oxidoreductase |
| 51445 |    | 33 |    |    | (Trans)glycosidases |
| 51556 |    | 25 |    |    | Metallo-dependent hydrolases |
| 51569 |    | 37 |    |    | Aldolase |
| 51604 |    | 14 |    |    | Enolase C-terminal domain-like |
| 51621 |    | 8 |    |    | Phosphoenolpyruvate/pyruvate domain |
| 51649 |    | 4 |    |    | RuBisCo, C-terminal domain |
| 51658 |    | 10 |    |    | Xylose isomerase-like |
| 51679 |    | 6 |    |    | Bacterial luciferase-like |
| 51690 |    | 7 |    |    | Nicotinate/Quinolinate PRTase C-terminal domain-like |
| 51695 |    | 7 |    |    | PLC-like phosphodiesterases |
| 51703 |    | 2 |    |    | Cobalamin (vitamin B12)-dependent enzymes |
| 51713 |    | 2 |    |    | tRNA-guanine transglycosylase |
| 51717 |    | 4 |    |    | Dihydropteroate synthetase-like |
| 51726 |    | 4 |    |    | UROD/MetE-like |
| 51730 |    | 2 |    |    | FAD-linked oxidoreductase |
| 51735 |    | 17 |    |    | NAD(P)-binding Rossmann-fold domains |
| 51971 |    | 9 |    |    | Nucleotide-binding domain |
| 51984 |    | 3 |    |    | MurCD N-terminal domain |
| 51989 |    | 3 |    |    | Glycosyl hydrolases family 6, cellulases |
| 51998 |    | 2 |    |    | PFL-like glycyl radical enzymes |
| 52009 |    | 2 |    |    | Phosphohistidine domain |
| 52016 |    | 5 |    |    | LeuD/IlvD-like |
| 52025 |    | 2 |    |    | PA domain |
| 52029 |    | 3 |    |    | GroEL apical domain-like |
| 52038 |    | 2 |    |    | Barstar-related |
| 52047 |    | 5 |    |    | RNI-like |
| 52058 |    | 19 |    |    | L domain-like |
| 52080 |    | 2 |    |    | Ribosomal proteins L15p and L18e |
| 52087 |    | 3 |    |    | CRAL/TRIO domain |
| 52091 |    | 3 |    |    | Anti-sigma factor antagonist SpoIIaa |
| 52096 |    | 23 |    |    | ClpP/crotonase |
| 52113 |    | 8 |    |    | BRCT domain |
| 52121 |    | 3 |    |    | Lumazine synthase |
| 52129 |    | 7 |    |    | Caspase-like |
| 52141 |    | 4 |    |    | Uracil-DNA glycosylase-like |
| 52151 |    | 2 |    |    | FabD/lysophospholipase-like |
| 52166 |    | 2 |    |    | Ribosomal protein L4 |
| 52172 |    | 29 |    |    | CheY-like |
| 52210 |    | 4 |    |    | Succinyl-CoA synthetase domains |
| 52218 |    | 20 |    |    | Flavoproteins |
| 52242 |    | 5 |    |    | Cobalamin (vitamin B12)-binding domain |
| 52266 |    | 8 |    |    | SGNH hydrolase |
| 52283 |    | 10 |    |    | Formate/glycerate dehydrogenase catalytic domain-like |
| 52304 |    | 2 |    |    | Type II 3-dehydroquinate dehydratase |
| 52309 |    | 6 |    |    | N-(deoxy)ribosyltransferase-like |
| 52313 |    | 2 |    |    | Ribosomal protein S2 |
| 52317 |    | 15 |    |    | Class I glutamine amidotransferase-like |
| 52335 |    | 5 |    |    | Methylglyoxal synthase-like |
| 52343 |    | 12 |    |    | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| 52374 |    | 17 |    |    | Nucleotidylyl transferase |
| 52402 |    | 19 |    |    | Adenine nucleotide alpha hydrolases-like |
| 52413 |    | 2 |    |    | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain |
| 52418 |    | 3 |    |    | Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain |
| 52425 |    | 5 |    |    | Cryptochrome/photolyase, N-terminal domain |
| 52440 |    | 15 |    |    | PreATP-grasp domain |
| 52467 |    | 12 |    |    | DHS-like NAD/FAD-binding domain |
| 52490 |    | 2 |    |    | Tubulin nucleotide-binding domain-like |
| 52499 |    | 6 |    |    | Isochorismatase-like hydrolases |
| 52507 |    | 4 |    |    | Homo-oligomeric flavin-containing Cys decarboxylases, HFCD |
| 52518 |    | 28 |    |    | Thiamin diphosphate-binding fold (THDP-binding) |
| 52540 |    | 45 |    |    | P-loop containing nucleoside triphosphate hydrolases |
| 52733 |    | 2 |    |    | Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) |
| 52743 |    | 7 |    |    | Subtilisin-like |
| 52768 |    | 7 |    |    | Arginase/deacetylase |
| 52777 |    | 4 |    |    | CoA-dependent acyltransferases |
| 52788 |    | 4 |    |    | Phosphotyrosine protein phosphatases I |
| 52794 |    | 2 |    |    | PTS system, Lactose/Cellobiose specific IIB subunit |
| 52799 |    | 19 |    |    | (Phosphotyrosine protein) phosphatases II |
| 52821 |    | 21 |    |    | Rhodanese/Cell cycle control phosphatase |
| 52922 |    | 6 |    |    | TK C-terminal domain-like |
| 52935 |    | 5 |    |    | PK C-terminal domain-like |
| 52943 |    | 2 |    |    | ATP synthase (F1-ATPase), gamma subunit |
| 52949 |    | 7 |    |    | Macro domain-like |
| 52954 |    | 12 |    |    | Class II aaRS ABD-related |
| 52968 |    | 3 |    |    | B12-dependent dehydatase associated subunit |
| 52972 |    | 7 |    |    | ITPase-like |
| 52980 |    | 7 |    |    | Restriction endonuclease-like |
| 53032 |    | 3 |    |    | tRNA-intron endonuclease catalytic domain-like |
| 53056 |    | 3 |    |    | beta-carbonic anhydrase, cab |
| 53067 |    | 23 |    |    | Actin-like ATPase domain |
| 53092 |    | 3 |    |    | Creatinase/prolidase N-terminal domain |
| 53098 |    | 2 |    |    | Ribonuclease H-like |
| 53137 |    | 4 |    |    | Translational machinery components |
| 53146 |    | 3 |    |    | Nitrogenase accessory factor-like |
| 53150 |    | 2 |    |    | DNA repair protein MutS, domain II |
| 53155 |    | 2 |    |    | Methylated DNA-protein cysteine methyltransferase domain |
| 53163 |    | 2 |    |    | HybD-like |
| 53167 |    | 11 |    |    | Purine and uridine phosphorylases |
| 53178 |    | 2 |    |    | Peptidyl-tRNA hydrolase-like |
| 53187 |    | 28 |    |    | Zn-dependent exopeptidases |
| 53218 |    | 8 |    |    | Molybdenum cofactor biosynthesis proteins |
| 53223 |    | 14 |    |    | Aminoacid dehydrogenase-like, N-terminal domain |
| 53244 |    | 7 |    |    | MurD-like peptide ligases, peptide-binding domain |
| 53254 |    | 9 |    |    | Phosphoglycerate mutase-like |
| 53271 |    | 26 |    |    | PRTase-like |
| 53300 |    | 13 |    |    | vWA-like |
| 53328 |    | 6 |    |    | Formyltransferase |
| 53383 |    | 38 |    |    | PLP-dependent transferases |
| 53448 |    | 22 |    |    | Nucleotide-diphospho-sugar transferases |
| 53474 |    | 43 |    |    | alpha/beta-Hydrolases |
| 53590 |    | 3 |    |    | Nucleoside hydrolase |
| 53597 |    | 14 |    |    | Dihydrofolate reductase-like |
| 53613 |    | 19 |    |    | Ribokinase-like |
| 53623 |    | 7 |    |    | MurD-like peptide ligases, catalytic domain |
| 53633 |    | 9 |    |    | Carbamate kinase-like |
| 53649 |    | 8 |    |    | Alkaline phosphatase-like |
| 53671 |    | 8 |    |    | Aspartate/ornithine carbamoyltransferase |
| 53681 |    | 4 |    |    | Aspartate/glutamate racemase |
| 53686 |    | 14 |    |    | Tryptophan synthase beta subunit-like PLP-dependent enzymes |
| 53697 |    | 6 |    |    | SIS domain |
| 53720 |    | 9 |    |    | ALDH-like |
| 53732 |    | 3 |    |    | Aconitase iron-sulfur domain |
| 53738 |    | 6 |    |    | Phosphoglucomutase, first 3 domains |
| 53743 |    | 2 |    |    | FucI/AraA N-terminal and middle domains |
| 53748 |    | 2 |    |    | Phosphoglycerate kinase |
| 53756 |    | 6 |    |    | UDP-Glycosyltransferase/glycogen phosphorylase |
| 53774 |    | 2 |    |    | Glutaminase/Asparaginase |
| 53784 |    | 2 |    |    | Phosphofructokinase |
| 53790 |    | 7 |    |    | Tetrapyrrole methylase |
| 53795 |    | 4 |    |    | PEP carboxykinase-like |
| 53800 |    | 4 |    |    | Chelatase |
| 53807 |    | 8 |    |    | "Helical backbone" metal receptor |
| 53822 |    | 10 |    |    | Periplasmic binding protein-like I |
| 53850 |    | 30 |    |    | Periplasmic binding protein-like II |
| 53901 |    | 22 |    |    | Thiolase-like |
| 53927 |    | 12 |    |    | Cytidine deaminase-like |
| 53933 |    | 4 |    |    | Microbial ribonucleases |
| 53955 |    | 12 |    |    | Lysozyme-like |
| 54060 |    | 7 |    |    | His-Me finger endonucleases |
| 54076 |    | 4 |    |    | RNase A-like |
| 54098 |    | 2 |    |    | Prion-like |
| 54106 |    | 2 |    |    | LysM domain |
| 54117 |    | 14 |    |    | Interleukin 8-like chemokines |
| 54160 |    | 17 |    |    | Chromo domain-like |
| 54171 |    | 5 |    |    | DNA-binding domain |
| 54184 |    | 2 |    |    | Penicillin-binding protein 2x (pbp-2x), c-terminal domain |
| 54189 |    | 5 |    |    | Ribosomal proteins S24e, L23 and L15e |
| 54197 |    | 8 |    |    | HIT-like |
| 54211 |    | 16 |    |    | Ribosomal protein S5 domain 2-like |
| 54236 |    | 25 |    |    | Ubiquitin-like |
| 54277 |    | 12 |    |    | CAD & PB1 domains |
| 54285 |    | 8 |    |    | MoaD/ThiS |
| 54292 |    | 18 |    |    | 2Fe-2S ferredoxin-like |
| 54328 |    | 4 |    |    | Staphylokinase/streptokinase |
| 54334 |    | 9 |    |    | Superantigen toxins, C-terminal domain |
| 54358 |    | 2 |    |    | Immunoglobulin-binding domains |
| 54373 |    | 15 |    |    | FAD-linked reductases, C-terminal domain |
| 54403 |    | 8 |    |    | Cystatin/monellin |
| 54416 |    | 9 |    |    | Amine oxidase N-terminal region |
| 54423 |    | 3 |    |    | DsbC/DsbG N-terminal domain-like |
| 54427 |    | 21 |    |    | NTF2-like |
| 54447 |    | 6 |    |    | ssDNA-binding transcriptional regulator domain |
| 54452 |    | 15 |    |    | MHC antigen-recognition domain |
| 54495 |    | 16 |    |    | UBC-like |
| 54506 |    | 10 |    |    | Diaminopimelate epimerase-like |
| 54511 |    | 3 |    |    | GFP-like |
| 54518 |    | 2 |    |    | Tubby C-terminal domain-like |
| 54523 |    | 7 |    |    | Pili subunits |
| 54529 |    | 2 |    |    | Mitochondrial glycoprotein MAM33-like |
| 54534 |    | 10 |    |    | FKBP-like |
| 54556 |    | 7 |    |    | Chitinase insertion domain |
| 54585 |    | 5 |    |    | Cdc48 domain 2-like |
| 54593 |    | 13 |    |    | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| 54631 |    | 20 |    |    | CBS-domain |
| 54637 |    | 45 |    |    | Thioesterase/thiol ester dehydrase-isomerase |
| 54654 |    | 3 |    |    | CI-2 family of serine protease inhibitors |
| 54665 |    | 6 |    |    | CO dehydrogenase molybdoprotein N-domain-like |
| 54675 |    | 8 |    |    | Nicotinate/Quinolinate PRTase N-terminal domain-like |
| 54680 |    | 3 |    |    | Pyrimidine nucleoside phosphorylase C-terminal domain |
| 54686 |    | 2 |    |    | Ribosomal protein L16p/L10e |
| 54695 |    | 8 |    |    | POZ domain |
| 54713 |    | 5 |    |    | Elongation factor Ts (EF-Ts), dimerisation domain |
| 54719 |    | 4 |    |    | Fe,Mn superoxide dismutase (SOD), C-terminal domain |
| 54736 |    | 2 |    |    | ClpS-like |
| 54747 |    | 2 |    |    | Ribosomal L11/L12e N-terminal domain |
| 54752 |    | 2 |    |    | RecA protein, C-terminal domain |
| 54762 |    | 2 |    |    | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
| 54768 |    | 16 |    |    | dsRNA-binding domain-like |
| 54786 |    | 2 |    |    | YcfA/nrd intein domain |
| 54791 |    | 19 |    |    | Eukaryotic type KH-domain (KH-domain type I) |
| 54806 |    | 2 |    |    | Alpha-lytic protease prodomain |
| 54814 |    | 7 |    |    | Prokaryotic type KH domain (KH-domain type II) |
| 54826 |    | 16 |    |    | Enolase N-terminal domain-like |
| 54843 |    | 2 |    |    | Ribosomal protein L22 |
| 54849 |    | 2 |    |    | GroEL-intermediate domain like |
| 54893 |    | 2 |    |    | Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain |
| 54897 |    | 6 |    |    | Protease propeptides/inhibitors |
| 54913 |    | 9 |    |    | GlnB-like |
| 54928 |    | 46 |    |    | RNA-binding domain, RBD |
| 54957 |    | 3 |    |    | Viral DNA-binding domain |
| 54966 |    | 4 |    |    | RuBisCO, large subunit, small (N-terminal) domain |
| 54975 |    | 7 |    |    | Acylphosphatase/BLUF domain-like |
| 54980 |    | 8 |    |    | EF-G C-terminal domain-like |
| 54984 |    | 2 |    |    | eEF-1beta-like |
| 54995 |    | 2 |    |    | Ribosomal protein S6 |
| 55008 |    | 12 |    |    | HMA, heavy metal-associated domain |
| 55021 |    | 23 |    |    | ACT-like |
| 55031 |    | 7 |    |    | Bacterial exopeptidase dimerisation domain |
| 55035 |    | 2 |    |    | NAD-binding domain of HMG-CoA reductase |
| 55048 |    | 2 |    |    | Probable ACP-binding domain of malonyl-CoA ACP transacylase |
| 55052 |    | 2 |    |    | CheY-binding domain of CheA |
| 55060 |    | 8 |    |    | GHMP Kinase, C-terminal domain |
| 55068 |    | 2 |    |    | Peptide methionine sulfoxide reductase |
| 55073 |    | 5 |    |    | Nucleotide cyclase |
| 55103 |    | 4 |    |    | FAD-linked oxidases, C-terminal domain |
| 55112 |    | 2 |    |    | Formylmethanofuran:tetrahydromethanopterin formyltransferase |
| 55116 |    | 2 |    |    | Formiminotransferase domain of formiminotransferase-cyclodeaminase. |
| 55120 |    | 7 |    |    | Pseudouridine synthase |
| 55124 |    | 2 |    |    | Sulfite reductase, domains 1 and 3 |
| 55129 |    | 2 |    |    | Ribosomal protein L30p/L7e |
| 55136 |    | 4 |    |    | Probable bacterial effector-binding domain |
| 55144 |    | 3 |    |    | LigT-like |
| 55154 |    | 4 |    |    | CYTH-like phosphatases |
| 55159 |    | 2 |    |    | eIF1-like |
| 55166 |    | 4 |    |    | Hedgehog/DD-peptidase |
| 55174 |    | 6 |    |    | Alpha-L RNA-binding motif |
| 55186 |    | 2 |    |    | ThrRS/AlaRS common domain |
| 55190 |    | 2 |    |    | Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain |
| 55194 |    | 2 |    |    | Ribosome recycling factor, RRF |
| 55205 |    | 3 |    |    | EPT/RTPC-like |
| 55221 |    | 2 |    |    | Yeast killer toxins |
| 55239 |    | 4 |    |    | RuBisCO, small subunit |
| 55248 |    | 2 |    |    | PCD-like |
| 55252 |    | 2 |    |    | C-terminal domain of arginine repressor |
| 55257 |    | 4 |    |    | RBP11-like subunits of RNA polymerase |
| 55261 |    | 3 |    |    | GAD domain |
| 55267 |    | 3 |    |    | tRNA-intron endonuclease N-terminal domain-like |
| 55271 |    | 2 |    |    | DNA repair protein MutS, domain I |
| 55277 |    | 2 |    |    | GYF domain |
| 55282 |    | 2 |    |    | Ribosomal protein L5 |
| 55298 |    | 5 |    |    | YjgF-like |
| 55307 |    | 5 |    |    | Tubulin C-terminal domain-like |
| 55315 |    | 7 |    |    | L30e-like |
| 55326 |    | 5 |    |    | PurM N-terminal domain-like |
| 55331 |    | 9 |    |    | Tautomerase/MIF |
| 55347 |    | 24 |    |    | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain |
| 55387 |    | 4 |    |    | Frataxin/Nqo15-like |
| 55394 |    | 2 |    |    | Bactericidal permeability-increasing protein, BPI |
| 55405 |    | 3 |    |    | RNA bacteriophage capsid protein |
| 55418 |    | 3 |    |    | eIF4e-like |
| 55424 |    | 12 |    |    | FAD/NAD-linked reductases, dimerisation (C-terminal) domain |
| 55447 |    | 5 |    |    | CO dehydrogenase flavoprotein C-terminal domain-like |
| 55455 |    | 2 |    |    | SRF-like |
| 55464 |    | 5 |    |    | Origin of replication-binding domain, RBD-like |
| 55486 |    | 18 |    |    | Metalloproteases ("zincins"), catalytic domain |
| 55545 |    | 7 |    |    | beta-N-acetylhexosaminidase-like domain |
| 55550 |    | 21 |    |    | SH2 domain |
| 55594 |    | 3 |    |    | HPr-like |
| 55608 |    | 12 |    |    | Homing endonucleases |
| 55620 |    | 12 |    |    | Tetrahydrobiopterin biosynthesis enzymes-like |
| 55658 |    | 2 |    |    | L9 N-domain-like |
| 55666 |    | 3 |    |    | Ribonuclease PH domain 2-like |
| 55676 |    | 2 |    |    | CytB endotoxin-like |
| 55681 |    | 19 |    |    | Class II aaRS and biotin synthetases |
| 55711 |    | 3 |    |    | Subdomain of clathrin and coatomer appendage domain |
| 55718 |    | 4 |    |    | Sterol carrier protein, SCP |
| 55729 |    | 48 |    |    | Acyl-CoA N-acyltransferases (Nat) |
| 55753 |    | 14 |    |    | Actin depolymerizing proteins |
| 55770 |    | 3 |    |    | Profilin (actin-binding protein) |
| 55781 |    | 5 |    |    | GAF domain-like |
| 55785 |    | 8 |    |    | PYP-like sensor domain (PAS domain) |
| 55797 |    | 4 |    |    | PR-1-like |
| 55804 |    | 4 |    |    | Phoshotransferase/anion transport protein |
| 55811 |    | 29 |    |    | Nudix |
| 55821 |    | 5 |    |    | YrdC/RibB |
| 55826 |    | 3 |    |    | YbaK/ProRS associated domain |
| 55831 |    | 3 |    |    | Thymidylate synthase/dCMP hydroxymethylase |
| 55846 |    | 8 |    |    | N-acetylmuramoyl-L-alanine amidase-like |
| 55856 |    | 5 |    |    | Cytochrome b5-like heme/steroid binding domain |
| 55874 |    | 9 |    |    | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| 55895 |    | 7 |    |    | Ribonuclease Rh-like |
| 55909 |    | 11 |    |    | Pentein |
| 55920 |    | 7 |    |    | Creatinase/aminopeptidase |
| 55945 |    | 5 |    |    | TATA-box binding protein-like |
| 55957 |    | 3 |    |    | Phosphoglucomutase, C-terminal domain |
| 55961 |    | 22 |    |    | Bet v1-like |
| 55979 |    | 22 |    |    | DNA clamp |
| 56003 |    | 5 |    |    | Molybdenum cofactor-binding domain |
| 56014 |    | 2 |    |    | Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 |
| 56024 |    | 10 |    |    | Phospholipase D/nuclease |
| 56029 |    | 3 |    |    | Monooxygenase (hydroxylase) regulatory protein |
| 56037 |    | 2 |    |    | PheT/TilS domain |
| 56042 |    | 6 |    |    | PurM C-terminal domain-like |
| 56047 |    | 2 |    |    | Ribosomal protein S8 |
| 56053 |    | 4 |    |    | Ribosomal protein L6 |
| 56059 |    | 14 |    |    | Glutathione synthetase ATP-binding domain-like |
| 56091 |    | 8 |    |    | DNA ligase/mRNA capping enzyme, catalytic domain |
| 56112 |    | 37 |    |    | Protein kinase-like (PK-like) |
| 56194 |    | 2 |    |    | Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain |
| 56204 |    | 2 |    |    | Hect, E3 ligase catalytic domain |
| 56214 |    | 3 |    |    | 4'-phosphopantetheinyl transferase |
| 56219 |    | 9 |    |    | DNase I-like |
| 56235 |    | 26 |    |    | N-terminal nucleophile aminohydrolases (Ntn hydrolases) |
| 56266 |    | 2 |    |    | DmpA/ArgJ-like |
| 56271 |    | 2 |    |    | Pyruvoyl-dependent histidine and arginine decarboxylases |
| 56276 |    | 3 |    |    | S-adenosylmethionine decarboxylase |
| 56281 |    | 19 |    |    | Metallo-hydrolase/oxidoreductase |
| 56300 |    | 16 |    |    | Metallo-dependent phosphatases |
| 56317 |    | 4 |    |    | Carbon-nitrogen hydrolase |
| 56322 |    | 6 |    |    | ADC synthase |
| 56327 |    | 13 |    |    | LDH C-terminal domain-like |
| 56349 |    | 7 |    |    | DNA breaking-rejoining enzymes |
| 56371 |    | 9 |    |    | Ribosome inactivating proteins (RIP) |
| 56399 |    | 3 |    |    | ADP-ribosylation |
| 56420 |    | 5 |    |    | Peptide deformylase |
| 56425 |    | 4 |    |    | Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain |
| 56436 |    | 21 |    |    | C-type lectin-like |
| 56487 |    | 2 |    |    | SRCR-like |
| 56496 |    | 3 |    |    | Fibrinogen C-terminal domain-like |
| 56507 |    | 2 |    |    | Methionine synthase activation domain-like |
| 56512 |    | 2 |    |    | Nitric oxide (NO) synthase oxygenase domain |
| 56519 |    | 2 |    |    | Penicillin binding protein dimerisation domain |
| 56524 |    | 2 |    |    | Oxidoreductase molybdopterin-binding domain |
| 56529 |    | 6 |    |    | FAH |
| 56534 |    | 2 |    |    | Aromatic aminoacid monoxygenases, catalytic and oligomerization domains |
| 56542 |    | 2 |    |    | Substrate-binding domain of HMG-CoA reductase |
| 56553 |    | 2 |    |    | Insert subdomain of RNA polymerase alpha subunit |
| 56574 |    | 11 |    |    | Serpins |
| 56601 |    | 24 |    |    | beta-lactamase/transpeptidase-like |
| 56634 |    | 3 |    |    | Heme-dependent catalase-like |
| 56645 |    | 10 |    |    | Acyl-CoA dehydrogenase NM domain-like |
| 56655 |    | 7 |    |    | Carbohydrate phosphatase |
| 56672 |    | 6 |    |    | DNA/RNA polymerases |
| 56712 |    | 3 |    |    | Prokaryotic type I DNA topoisomerase |
| 56719 |    | 2 |    |    | Type II DNA topoisomerase |
| 56731 |    | 2 |    |    | DNA primase core |
| 56747 |    | 4 |    |    | Prim-pol domain |
| 56752 |    | 4 |    |    | D-aminoacid aminotransferase-like PLP-dependent enzymes |
| 56762 |    | 3 |    |    | HydB/Nqo4-like |
| 56770 |    | 2 |    |    | HydA/Nqo6-like |
| 56784 |    | 44 |    |    | HAD-like |
| 56796 |    | 7 |    |    | Dehydroquinate synthase-like |
| 56801 |    | 3 |    |    | Acetyl-CoA synthetase-like |
| 56808 |    | 3 |    |    | Ribosomal protein L1 |
| 56815 |    | 2 |    |    | Sec1/munc18-like (SM) proteins |
| 56837 |    | 2 |    |    | Colicin |
| 56849 |    | 3 |    |    | delta-Endotoxin (insectocide), N-terminal domain |
| 56854 |    | 9 |    |    | Bcl-2 inhibitors of programmed cell death |
| 56918 |    | 6 |    |    | Light-harvesting complex subunits |
| 56925 |    | 4 |    |    | OMPA-like |
| 56935 |    | 6 |    |    | Porins |
| 56954 |    | 2 |    |    | Outer membrane efflux proteins (OEP) |
| 56959 |    | 2 |    |    | Leukocidin-like |
| 56973 |    | 2 |    |    | Aerolisin/ETX pore-forming domain |
| 56983 |    | 2 |    |    | Viral glycoprotein, central and dimerisation domains |
| 56994 |    | 3 |    |    | Insulin-like |
| 57016 |    | 3 |    |    | Plant lectins/antimicrobial peptides |
| 57027 |    | 3 |    |    | Plant inhibitors of proteinases and amylases |
| 57048 |    | 3 |    |    | Gurmarin-like |
| 57059 |    | 13 |    |    | omega toxin-like |
| 57095 |    | 26 |    |    | Scorpion toxin-like |
| 57184 |    | 2 |    |    | Growth factor receptor domain |
| 57190 |    | 4 |    |    | Colipase-like |
| 57196 |    | 23 |    |    | EGF/Laminin |
| 57247 |    | 2 |    |    | Bowman-Birk inhibitor, BBI |
| 57262 |    | 5 |    |    | Leech antihemostatic proteins |
| 57283 |    | 2 |    |    | PMP inhibitors |
| 57288 |    | 2 |    |    | Midkine |
| 57302 |    | 14 |    |    | Snake toxin-like |
| 57362 |    | 9 |    |    | BPTI-like |
| 57392 |    | 13 |    |    | Defensin-like |
| 57414 |    | 3 |    |    | Hairpin loop containing domain-like |
| 57424 |    | 6 |    |    | LDL receptor-like module |
| 57429 |    | 2 |    |    | Crambin-like |
| 57440 |    | 6 |    |    | Kringle-like |
| 57492 |    | 2 |    |    | Trefoil |
| 57501 |    | 10 |    |    | Cystine-knot cytokines |
| 57535 |    | 27 |    |    | Complement control module/SCR domain |
| 57546 |    | 3 |    |    | Crisp domain-like |
| 57552 |    | 2 |    |    | Blood coagulation inhibitor (disintegrin) |
| 57567 |    | 4 |    |    | Serine protease inhibitors |
| 57581 |    | 3 |    |    | TB module/8-cys domain |
| 57603 |    | 6 |    |    | FnI-like domain |
| 57610 |    | 2 |    |    | Thyroglobulin type-1 domain |
| 57625 |    | 2 |    |    | Invertebrate chitin-binding proteins |
| 57630 |    | 3 |    |    | GLA-domain |
| 57652 |    | 5 |    |    | HIPIP (high potential iron protein) |
| 57667 |    | 42 |    |    | C2H2 and C2HC zinc fingers |
| 57701 |    | 5 |    |    | Zn2/Cys6 DNA-binding domain |
| 57716 |    | 22 |    |    | Glucocorticoid receptor-like (DNA-binding domain) |
| 57756 |    | 4 |    |    | Retrovirus zinc finger-like domains |
| 57774 |    | 3 |    |    | Microbial and mitochondrial ADK, insert "zinc finger" domain |
| 57783 |    | 13 |    |    | Zinc beta-ribbon |
| 57802 |    | 6 |    |    | Rubredoxin-like |
| 57825 |    | 2 |    |    | Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain |
| 57829 |    | 6 |    |    | Zn-binding ribosomal proteins |
| 57850 |    | 10 |    |    | RING/U-box |
| 57863 |    | 2 |    |    | ArfGap/RecO-like zinc finger |
| 57868 |    | 9 |    |    | Metallothionein |
| 57889 |    | 5 |    |    | Cysteine-rich domain |
| 57903 |    | 11 |    |    | FYVE/PHD zinc finger |
| 57917 |    | 2 |    |    | Zn-binding domains of ADDBP |
| 57924 |    | 4 |    |    | Inhibitor of apoptosis (IAP) repeat |
| 57933 |    | 2 |    |    | TAZ domain |
| 57938 |    | 2 |    |    | DnaJ/Hsp40 cysteine-rich domain |
| 63380 |    | 14 |    |    | Riboflavin synthase domain-like |
| 63393 |    | 2 |    |    | RNA polymerase subunits |
| 63411 |    | 20 |    |    | LuxS/MPP-like metallohydrolase |
| 63418 |    | 2 |    |    | MurE/MurF N-terminal domain |
| 63446 |    | 2 |    |    | Type I dockerin domain |
| 63451 |    | 3 |    |    | LEM domain |
| 63491 |    | 3 |    |    | BAG domain |
| 63520 |    | 2 |    |    | PTS-regulatory domain, PRD |
| 63562 |    | 2 |    |    | RPB6/omega subunit-like |
| 63570 |    | 4 |    |    | PABC (PABP) domain |
| 63600 |    | 2 |    |    | Telomeric repeat binding factor (TRF) dimerisation domain |
| 63724 |    | 2 |    |    | Cytolysin/lectin |
| 63748 |    | 10 |    |    | Tudor/PWWP/MBT |
| 63763 |    | 3 |    |    | SAND domain-like |
| 63817 |    | 3 |    |    | Sortase |
| 63825 |    | 2 |    |    | YWTD domain |
| 63829 |    | 4 |    |    | Calcium-dependent phosphotriesterase |
| 63862 |    | 2 |    |    | Thiamin pyrophosphokinase, substrate-binding domain |
| 63867 |    | 4 |    |    | MoeA C-terminal domain-like |
| 63882 |    | 3 |    |    | MoeA N-terminal region -like |
| 63887 |    | 2 |    |    | P-domain of calnexin/calreticulin |
| 63965 |    | 2 |    |    | Precorrin-8X methylmutase CbiC/CobH |
| 63999 |    | 2 |    |    | Thiamin pyrophosphokinase, catalytic domain |
| 64005 |    | 2 |    |    | Undecaprenyl diphosphate synthase |
| 64076 |    | 3 |    |    | MTH938-like |
| 64153 |    | 2 |    |    | YjeF N-terminal domain-like |
| 64167 |    | 2 |    |    | SurE-like |
| 64182 |    | 2 |    |    | DHH phosphoesterases |
| 64268 |    | 5 |    |    | PX domain |
| 64288 |    | 2 |    |    | Chorismate lyase-like |
| 64307 |    | 3 |    |    | SirA-like |
| 64356 |    | 5 |    |    | SNARE-like |
| 64397 |    | 2 |    |    | Hsp33 domain |
| 64438 |    | 3 |    |    | CNF1/YfiH-like putative cysteine hydrolases |
| 64496 |    | 2 |    |    | DNA-binding domain of intron-encoded endonucleases |
| 64586 |    | 3 |    |    | C-terminal domain of ProRS |
| 68906 |    | 6 |    |    | SAP domain |
| 68923 |    | 4 |    |    | PEP carboxykinase N-terminal domain |
| 69000 |    | 2 |    |    | FAD-dependent thiol oxidase |
| 69012 |    | 2 |    |    | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| 69055 |    | 2 |    |    | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
| 69125 |    | 2 |    |    | Nuclear receptor coactivator interlocking domain |
| 69179 |    | 4 |    |    | Integrin domains |
| 69189 |    | 3 |    |    | Penicillin-binding protein associated domain |
| 69203 |    | 2 |    |    | Nucleoplasmin-like core domain |
| 69287 |    | 2 |    |    | Urease metallochaperone UreE, N-terminal domain |
| 69298 |    | 2 |    |    | Quinohemoprotein amine dehydrogenase A chain, domain 3 |
| 69340 |    | 2 |    |    | C-terminal domain of adenylylcyclase associated protein |
| 69349 |    | 3 |    |    | Phage fibre proteins |
| 69360 |    | 2 |    |    | Cell wall binding repeat |
| 69369 |    | 2 |    |    | Cloacin translocation domain |
| 69500 |    | 2 |    |    | DTD-like |
| 69572 |    | 3 |    |    | Activating enzymes of the ubiquitin-like proteins |
| 69618 |    | 2 |    |    | HemD-like |
| 69635 |    | 9 |    |    | Type III secretory system chaperone |
| 69645 |    | 3 |    |    | Arp2/3 complex subunits |
| 69695 |    | 3 |    |    | SRP19 |
| 69705 |    | 2 |    |    | Transcription factor NusA, N-terminal domain |
| 69737 |    | 2 |    |    | Urease metallochaperone UreE, C-terminal domain |
| 69765 |    | 2 |    |    | IpsF-like |
| 69786 |    | 2 |    |    | YggU-like |
| 69819 |    | 2 |    |    | MTH1598-like |
| 69864 |    | 2 |    |    | Argininosuccinate synthetase, C-terminal domain |
| 69917 |    | 2 |    |    | OMPT-like |
| 74653 |    | 3 |    |    | TolA/TonB C-terminal domain |
| 74877 |    | 2 |    |    | Major surface antigen p30, SAG1 |
| 74924 |    | 8 |    |    | Cap-Gly domain |
| 75138 |    | 2 |    |    | HPr kinase/phoshatase HprK N-terminal domain |
| 75169 |    | 8 |    |    | DsrEFH-like |
| 75217 |    | 13 |    |    | alpha/beta knot |
| 75304 |    | 4 |    |    | Amidase signature (AS) enzymes |
| 75399 |    | 2 |    |    | Plakin repeat |
| 75445 |    | 2 |    |    | D-ribose-5-phosphate isomerase (RpiA), lid domain |
| 75471 |    | 2 |    |    | YhbY-like |
| 75615 |    | 2 |    |    | Siroheme synthase middle domains-like |
| 75620 |    | 2 |    |    | Release factor |
| 75625 |    | 2 |    |    | YebC-like |
| 81271 |    | 4 |    |    | TGS-like |
| 81273 |    | 2 |    |    | H-NS histone-like proteins |
| 81296 |    | 40 |    |    | E set domains |
| 81301 |    | 13 |    |    | Nucleotidyltransferase |
| 81321 |    | 5 |    |    | Family A G protein-coupled receptor-like |
| 81324 |    | 3 |    |    | Voltage-gated potassium channels |
| 81338 |    | 3 |    |    | Aquaporin-like |
| 81343 |    | 5 |    |    | Fumarate reductase respiratory complex transmembrane subunits |
| 81383 |    | 3 |    |    | F-box domain |
| 81452 |    | 2 |    |    | Cytochrome c oxidase subunit III-like |
| 81464 |    | 3 |    |    | Cytochrome c oxidase subunit II-like, transmembrane region |
| 81483 |    | 2 |    |    | Bacterial photosystem II reaction centre, L and M subunits |
| 81490 |    | 3 |    |    | Photosystem II reaction centre subunit H, transmembrane region |
| 81502 |    | 4 |    |    | ISP transmembrane anchor |
| 81508 |    | 2 |    |    | Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| 81514 |    | 2 |    |    | Subunit X (non-heme 7 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| 81524 |    | 2 |    |    | 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| 81531 |    | 2 |    |    | Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| 81585 |    | 3 |    |    | DNA polymerase beta-like, second domain |
| 81593 |    | 5 |    |    | Nucleotidyltransferase substrate binding subunit/domain |
| 81606 |    | 2 |    |    | PP2C-like |
| 81624 |    | 6 |    |    | N-terminal domain of MutM-like DNA repair proteins |
| 81631 |    | 4 |    |    | PAP/OAS1 substrate-binding domain |
| 81648 |    | 2 |    |    | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| 81660 |    | 4 |    |    | Metal cation-transporting ATPase, ATP-binding domain N |
| 81698 |    | 2 |    |    | FF domain |
| 81736 |    | 2 |    |    | Group V grass pollen allergen |
| 81811 |    | 2 |    |    | Helical domain of Sec23/24 |
| 81853 |    | 2 |    |    | Family 10 polysaccharide lyase |
| 81886 |    | 2 |    |    | Helical scaffold and wing domains of SecA |
| 81891 |    | 3 |    |    | Poly A polymerase C-terminal region-like |
| 81901 |    | 2 |    |    | HCP-like |
| 81923 |    | 3 |    |    | Double Clp-N motif |
| 81986 |    | 2 |    |    | Tp47 lipoprotein, middle and C-terminal domains |
| 81995 |    | 2 |    |    | beta-sandwich domain of Sec23/24 |
| 82057 |    | 4 |    |    | Prokaryotic SH3-related domain |
| 82109 |    | 2 |    |    | MIR domain |
| 82114 |    | 2 |    |    | Riboflavin kinase-like |
| 82153 |    | 3 |    |    | FAS1 domain |
| 82171 |    | 2 |    |    | DPP6 N-terminal domain-like |
| 82199 |    | 4 |    |    | SET domain |
| 82282 |    | 2 |    |    | Homocysteine S-methyltransferase |
| 82549 |    | 4 |    |    | DAK1/DegV-like |
| 82649 |    | 5 |    |    | SufE/NifU |
| 82657 |    | 2 |    |    | BolA-like |
| 82679 |    | 2 |    |    | N-utilization substance G protein NusG, N-terminal domain |
| 82693 |    | 4 |    |    | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| 82697 |    | 3 |    |    | PurS-like |
| 82704 |    | 3 |    |    | AlbA-like |
| 82708 |    | 3 |    |    | R3H domain |
| 82714 |    | 2 |    |    | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains |
| 82754 |    | 2 |    |    | C-terminal, gelsolin-like domain of Sec23/24 |
| 82784 |    | 5 |    |    | OsmC-like |
| 82829 |    | 2 |    |    | MesJ substrate recognition domain-like |
| 82866 |    | 2 |    |    | Multidrug efflux transporter AcrB transmembrane domain |
| 82919 |    | 2 |    |    | Zn-finger domain of Sec23/24 |
| 88633 |    | 25 |    |    | Positive stranded ssRNA viruses |
| 88645 |    | 7 |    |    | ssDNA viruses |
| 88648 |    | 2 |    |    | Group I dsDNA viruses |
| 88650 |    | 3 |    |    | Satellite viruses |
| 88659 |    | 7 |    |    | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| 88688 |    | 5 |    |    | Families 57/38 glycoside transferase middle domain |
| 88697 |    | 12 |    |    | PUA domain-like |
| 88713 |    | 13 |    |    | Glycoside hydrolase/deacetylase |
| 88798 |    | 2 |    |    | N-terminal, heterodimerisation domain of RBP7 (RpoE) |
| 88802 |    | 4 |    |    | Pre-PUA domain |
| 89000 |    | 3 |    |    | post-HMGL domain-like |
| 89009 |    | 3 |    |    | GAT-like domain |
| 89028 |    | 3 |    |    | Cobalamin adenosyltransferase-like |
| 89095 |    | 3 |    |    | GatB/YqeY motif |
| 89155 |    | 2 |    |    | TorD-like |
| 89360 |    | 2 |    |    | HesB-like domain |
| 89392 |    | 3 |    |    | Prokaryotic lipoproteins and lipoprotein localization factors |
| 89447 |    | 3 |    |    | AbrB/MazE/MraZ-like |
| 89550 |    | 3 |    |    | PHP domain-like |
| 89623 |    | 2 |    |    | Ribose/Galactose isomerase RpiB/AlsB |
| 89733 |    | 3 |    |    | L-sulfolactate dehydrogenase-like |
| 89796 |    | 3 |    |    | CoA-transferase family III (CaiB/BaiF) |
| 89872 |    | 2 |    |    | Inhibitor of vertebrate lysozyme, Ivy |
| 89895 |    | 2 |    |    | FYSH domain |
| 89919 |    | 2 |    |    | Ribosome-binding factor A, RbfA |
| 89957 |    | 6 |    |    | MTH1187/YkoF-like |
| 89963 |    | 2 |    |    | YajQ-like |
| 90096 |    | 2 |    |    | Subunits of heterodimeric actin filament capping protein Capz |
| 90112 |    | 2 |    |    | Neurotransmitter-gated ion-channel transmembrane pore |
| 90123 |    | 2 |    |    | ABC transporter transmembrane region |
| 90209 |    | 4 |    |    | Ran BP2/NZF zinc finger-like |
| 90229 |    | 3 |    |    | CCCH zinc finger |