Pfam Domains mapped on to the structure: 5CSC

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00285	Citrate synthase	PF00285	PF00285
2	B	PF00285	Citrate synthase	PF00285	PF00285

Conserved Domain Database Superfamily Annotations: 5CSC

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	5CSC	99858	cd06105	ScCit1-2_like -	cl00416
2	5CSC	199305	cl00416	CS_ACL-C_CCL	superfamily - -
3	5CSC	199305	cl00416	CS_ACL-C_CCL	superfamily - -

Structural Details of PDB entry 5CSC PDBid Chains Hinge Swapped Domain 5CSC A,B A:417-426,B:417-426 A:427-433,B:427-433 Swapped-domain interface residues and interactions: Chains Residues A 52, 54, 427, 428, 430, 431, 433, B 52, 54, 427, 428, 430, 431, Non-swapped-domain interface residues and interactions: Chains Residues A 20, 21, 24, 25, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 53, 57, 58, 123, 126, 127, 130, 131, 132, 134, 135, 139, 142, 143, 146, 147, 149, 150, 158, 239, 241, 243, 246, 247, 250, 251, 253, 254, 255, 256, 260, 263, 264, 267, 268, 270, 271, 272, 273, 276, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426, B 20, 21, 24, 25, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 53, 57, 123, 126, 127, 130, 131, 132, 134, 135, 139, 142, 143, 146, 147, 149, 150, 158, 164, 239, 241, 243, 246, 247, 250, 251, 253, 254, 255, 256, 260, 263, 264, 267, 268, 270, 271, 272, 273, 276, 417, 418, 419, 420, 421, 422, 423, 424, 425, 426,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:5CSC

B:5CSC

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	5CSC.ali
atm file:	5CSC.atm
cof file:	5CSC.cof
hbd file:	5CSC.hbd
html file:	5CSC.html
pdb file:	5CSC.pdb
ps file:	5CSC.ps
psa file:	5CSC.psa
rtf file:	5CSC.rtf
sst file:	5CSC.sst
tem file:	5CSC.tem