Pfam Domains mapped on to the structure: 3F3S

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF02737	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	PF02737	PF02737
2	A	PF00725	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	PF00725	PF00725

Gene Ontology Annotations: 3F3S

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0055114	oxidation-reduction process	GO:0055114

Conserved Domain Database Superfamily Annotations: 3F3S

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	3F3S	212616	cl09931	NADB_Rossmann	superfamily - -
2	3F3S	201415	cl08285	3HCDH	superfamily - -
3	3F3S	201415	cl08285	3HCDH	superfamily - -

Structural Details of PDB entry 3F3S PDBid Chains Hinge Swapped Domain 3F3S A,B A:232-237,B:232-237 A:238-316,B:238-316 Swapped-domain interface residues and interactions: Chains Residues A 191, 192, 197, 200, 221, 230, 238, 239, 240, 241, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 258, 259, 260, 261, 262, 263, 264, 265, 266, 269, 271, 272, 274, 277, 278, 280, 281, 284, 288, 290, 292, 295, 298, 299, 301, 302, 305, 306, 308, 309, 310, 312, 313, 315, 316, B 191, 197, 200, 203, 221, 230, 231, 238, 239, 240, 241, 242, 243, 244, 246, 247, 248, 249, 251, 252, 253, 255, 256, 258, 259, 260, 261, 262, 263, 264, 265, 266, 269, 271, 272, 274, 277, 278, 280, 281, 284, 288, 290, 295, 298, 299, 301, 302, 305, 306, 308, 309, 310, 312, 313, Non-swapped-domain interface residues and interactions: Chains Residues A 147, 148, 153, 154, 155, 182, 184, 185, 186, 187, 188, 190, 194, 195, 198, 199, 201, 202, 203, 204, 205, 206, 207, 209, 212, 213, 214, 215, 219, 220, 222, 223, 224, 225, 226, 227, 228, 229, 231, 232, 233, 234, 235, 236, 237, B 97, 124, 125, 130, 147, 148, 153, 154, 155, 182, 184, 186, 187, 188, 190, 194, 195, 198, 199, 201, 202, 204, 205, 206, 207, 209, 212, 213, 214, 215, 216, 219, 220, 222, 223, 224, 225, 226, 227, 228, 229, 232, 233, 234, 235, 236, 237,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:3F3S

B:3F3S

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	3F3S.ali
atm file:	3F3S.atm
cof file:	3F3S.cof
hbd file:	3F3S.hbd
html file:	3F3S.html
pdb file:	3F3S.pdb
ps file:	3F3S.ps
psa file:	3F3S.psa
rtf file:	3F3S.rtf
sst file:	3F3S.sst
tem file:	3F3S.tem