3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 3DVG

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF13895 Immunoglobulin domain PF13895 PF13895

2 A PF13895 Immunoglobulin domain PF13895 PF13895

3 A PF13927 Immunoglobulin domain PF13927 PF13927

4 A PF13927 Immunoglobulin domain PF13927 PF13927

5 A PF00047 Immunoglobulin domain PF00047 PF00047

6 B PF13927 Immunoglobulin domain PF13927 PF13927

7 X PF00240 Ubiquitin family PF00240 PF00240

8 Y PF00240 Ubiquitin family PF00240 PF00240

Conserved Domain Database Superfamily Annotations: 3DVG

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 3DVG 176398 cd01803 Ubiquitin - cl00155

2 3DVG 212176 cl00155 UBQ superfamily - -

3 3DVG 212176 cl00155 UBQ superfamily - -

Structural Details of PDB entry 3DVG

Structural Details of PDB entry 3DVG

PDBid Chains Hinge Swapped Domain

3DVG A,B A:41-44,B:42-45 A:5-40,B:1-41

Swapped-domain interface residues and interactions:

Chains Residues
A 5, 6, 7, 8, 32, 34, 36, 38,

B 35, 37, 39, 42, 43, 44, 104, 105, 106,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 41, 42, 43, 44, 46, 49, 50, 55, 56, 87, 89, 91, 96, 97, 98, 100, 116, 118, 119, 120, 121, 123, 125, 126, 129, 131, 133, 135, 137, 139, 140, 162, 163, 164, 165, 166, 169, 176, 178, 180, 182, 209, 210, 211, 214,

B 45, 46, 47, 50, 59, 60, 62, 95, 102, 103, 107, 108, 110, 112, 129, 130, 131, 132, 136, 137, 138, 139, 144, 148, 150, 171, 173, 174, 176, 178, 179, 186, 188, 190, 216,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:3DVG B:3DVG

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 3DVG.ali
atm file: 3DVG.atm
cof file: 3DVG.cof
hbd file: 3DVG.hbd
html file: 3DVG.html
pdb file: 3DVG.pdb
ps file: 3DVG.ps
psa file: 3DVG.psa
rtf file: 3DVG.rtf
sst file: 3DVG.sst
tem file: 3DVG.tem