Pfam Domains mapped on to the structure: 3DCX
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF08000
Protein of unknown function (DUF1696)
PF08000
PF08000
Conserved Domain Database Superfamily Annotations: 3DCX
Structural Details of PDB entry 3DCX
Structural Details of PDB entry 3DCX
PDBid
Chains
Hinge
Swapped Domain
3DCX
A,D,C,E,B
A:108-110,D:108-110,C:108-110,E:108-110,B:108-110
A:111-124,D:111-124,C:111-124,E:111-124,B:111-124
Swapped-domain interface residues and interactions:
Chains
Residues
A
25 , 26 , 28 , 29 , 49 , 70 , 113 , 116 , 117 , 120 , 121 , 123 , 124 ,
B
25 , 26 , 28 , 29 , 49 , 70 , 113 , 116 , 117 , 120 , 121 , 123 , 124 ,
C
25 , 26 , 28 , 29 , 113 , 116 , 117 , 120 , 121 , 124 ,
D
25 , 26 , 28 , 29 , 49 , 113 , 116 , 117 , 120 , 121 ,
E
25 , 26 , 28 , 29 , 49 , 70 , 113 , 116 , 117 , 120 , 121 , 124 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
24 , 50 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 72 , 73 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 94 , 95 , 96 , 97 , 98 , 99 ,
B
24 , 50 , 57 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 85 , 86 , 95 , 96 , 97 , 98 , 99 , 100 ,
C
24 , 30 , 49 , 50 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 70 , 73 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 94 , 95 , 96 , 97 , 98 , 99 ,
D
24 , 50 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 70 , 73 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 83 , 94 , 95 , 96 , 97 , 98 , 99 , 100 ,
E
24 , 50 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 72 , 73 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 94 , 95 , 96 , 97 , 98 , 99 , 100 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
D No mutation No mutation No mutation No mutation
C No mutation No mutation No mutation No mutation
E No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: