3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 3D8B

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00004 ATPase family associated with various cellular activities (AAA) PF00004 PF00004

2 A PF09336 Vps4 C terminal oligomerisation domain PF09336 PF09336

Gene Ontology Annotations: 3D8B

No. GO ID GO Description Linkout - AmiGO

1 GO:0005524 ATP binding GO:0005524

Conserved Domain Database Superfamily Annotations: 3D8B

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 3D8B 99707 cd00009 AAA - cl09099

2 3D8B 212613 cl09099 P-loop_NTPase superfamily - -

3 3D8B 204202 Vps4_C superfamily N -

4 3D8B 204202 Vps4_C superfamily N -

Structural Details of PDB entry 3D8B

Structural Details of PDB entry 3D8B

PDBid Chains Hinge Swapped Domain

3D8B A,B A:565-569,B:565-569;A:655-660,B:655-660 A:570-654,B:570-654

Swapped-domain interface residues and interactions:

Chains Residues
A 426, 580, 583, 584, 609, 613, 617, 620, 621, 623, 625, 636,

B 426, 580, 583, 584, 609, 613, 617, 620, 621, 623, 625, 629, 631, 633,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 382, 386, 389, 390, 391, 395, 396, 397, 399, 401, 402, 414, 419, 422, 423, 431, 449, 452, 456, 457, 459, 460, 466, 468, 469, 471, 472, 473, 674,

B 380, 382, 385, 386, 389, 390, 391, 395, 396, 397, 399, 401, 402, 419, 422, 423, 449, 452, 456, 457, 459, 466, 468, 469, 471,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:3D8B B:3D8B

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 3D8B.ali
atm file: 3D8B.atm
cof file: 3D8B.cof
hbd file: 3D8B.hbd
html file: 3D8B.html
pdb file: 3D8B.pdb
ps file: 3D8B.ps
psa file: 3D8B.psa
rtf file: 3D8B.rtf
sst file: 3D8B.sst
tem file: 3D8B.tem