Pfam Domains mapped on to the structure: 3D2R
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF10436
Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
PF10436
PF10436
2
A
PF02518
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
PF02518
PF02518
Conserved Domain Database Superfamily Annotations: 3D2R
Structural Details of PDB entry 3D2R
Structural Details of PDB entry 3D2R
PDBid
Chains
Hinge
Swapped Domain
3D2R
A,B
A:373-375,B:373-375
A:376-397,B:376-397
Swapped-domain interface residues and interactions:
Chains
Residues
A
374 , 375 , 376 , 377 , 379 , 381 , 393 , 394 , 395 , 396 , 397 ,
B
374 , 375 , 376 , 377 , 379 , 381 , 385 , 394 , 395 , 396 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
34 , 157 , 160 , 161 , 164 , 230 , 232 , 279 , 281 , 283 , 285 , 286 , 288 , 290 , 299 , 300 , 301 , 345 , 347 , 349 , 351 , 352 , 353 , 354 , 355 , 356 , 359 , 361 , 363 , 365 ,
B
34 , 157 , 160 , 161 , 164 , 230 , 232 , 279 , 281 , 283 , 285 , 286 , 288 , 290 , 299 , 300 , 301 , 345 , 347 , 351 , 352 , 353 , 354 , 355 , 356 , 359 , 361 , 363 , 365 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: