Pfam Domains mapped on to the structure: 3D1L

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF01488	Shikimate / quinate 5-dehydrogenase	PF01488	PF01488
2	A	PF03446	NAD binding domain of 6-phosphogluconate dehydrogenase	PF03446	PF03446
3	A	PF03807	NADP oxidoreductase coenzyme F420-dependent	PF03807	PF03807
4	A	PF00106	short chain dehydrogenase	PF00106	PF00106
5	A	PF10728	Domain of unknown function (DUF2520)	PF10728	PF10728

Conserved Domain Database Superfamily Annotations: 3D1L

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	3D1L	212616	NADB_Rossmann	superfamily	N -
2	3D1L	204549	cl11323	DUF2520	superfamily - -

Structural Details of PDB entry 3D1L PDBid Chains Hinge Swapped Domain 3D1L A,B A:162-165,B:162-165 A:166-263,B:166-263 Swapped-domain interface residues and interactions: Chains Residues A 122, 135, 166, 167, 170, 171, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 186, 187, 188, 189, 190, 191, 192, 193, 196, 198, 200, 201, 202, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 219, 220, 221, 222, 223, 224, 225, 226, 231, 233, 234, 237, 238, 242, 245, 247, 250, 251, 252, 254, 255, 256, 258, 259, 262, 263, B 101, 121, 122, 124, 126, 133, 135, 159, 167, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 186, 187, 188, 189, 190, 191, 192, 193, 196, 197, 198, 199, 200, 201, 202, 204, 205, 206, 207, 208, 209, 210, 211, 214, 215, 219, 220, 222, 223, 224, 225, 226, 238, 242, 245, 247, 250, 251, 252, 254, 255, 256, 258, 259, Non-swapped-domain interface residues and interactions: Chains Residues A 123, 133, 137, 159, 161, B 17, 75, 123, 127, 129,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:3D1L

B:3D1L

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	3D1L.ali
atm file:	3D1L.atm
cof file:	3D1L.cof
hbd file:	3D1L.hbd
html file:	3D1L.html
pdb file:	3D1L.pdb
ps file:	3D1L.ps
psa file:	3D1L.psa
rtf file:	3D1L.rtf
sst file:	3D1L.sst
tem file:	3D1L.tem