Pfam Domains mapped on to the structure: 3CYY

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00595	PDZ domain (Also known as DHR or GLGF)	PF00595	PF00595

Structural Details of PDB entry 3CYY PDBid Chains Hinge Swapped Domain 3CYY A,D,C,B A:198-202,D:198-202,C:198-202,B:198-202 A:183-197,D:183-197,C:183-197,B:183-197 Swapped-domain interface residues and interactions: Chains Residues A 183, 184, 185, 186, 187, 188, 189, 190, 191, 194, 196, 207, 217, 220, 221, 222, 254, 255, 256, 257, 258, 259, 260, 261, B 183, 184, 185, 186, 187, 188, 189, 190, 191, 196, 197, 217, 222, 253, 254, 255, 256, 257, 258, 259, 260, 261, Non-swapped-domain interface residues and interactions: Chains Residues A 198, 199, 200, 201, 202, 203, 204, 205, 206, 208, 209, 210, 212, 215, 216, 223, 230, 238, 239, 241, 242, 249, 262, B 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 212, 215, 216, 220, 223, 230, 238, 239, 241, 242, 249, 262,

Swapped domains are represented using trasperent spheres. Non-swapped part is reprented using light color and cartoon reprentation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	ALA(193)ARG,
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	ALA(193)ARG,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

3:3CYY

A:3CYY

B:3CYY

C:3CYY

D:3CYY

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	3CYY.ali
atm file:	3CYY.atm
cof file:	3CYY.cof
hbd file:	3CYY.hbd
html file:	3CYY.html
pdb file:	3CYY.pdb
ps file:	3CYY.ps
psa file:	3CYY.psa
rtf file:	3CYY.rtf
sst file:	3CYY.sst
tem file:	3CYY.tem