3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 3CBU

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF13417 Glutathione S-transferase, N-terminal domain PF13417 PF13417

2 A PF13409 Glutathione S-transferase, N-terminal domain PF13409 PF13409

3 A PF13410 Glutathione S-transferase, C-terminal domain PF13410 PF13410

Conserved Domain Database Superfamily Annotations: 3CBU

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 3CBU 198344 cd10424 GST_C_9 - cl02776

2 3CBU 207726 cl02776 GST_C_family superfamily - -

3 3CBU 48493 cd00570 GST_N_family - cl00388

4 3CBU 212209 cl00388 Thioredoxin_like superfamily - -

5 3CBU 212209 cl00388 Thioredoxin_like superfamily - -

Structural Details of PDB entry 3CBU

Structural Details of PDB entry 3CBU

PDBid Chains Hinge Swapped Domain

3CBU A,B A:56-58,B:56-58;A:77-79,B:77-79 A:59-76,B:59-76

Swapped-domain interface residues and interactions:

Chains Residues
A 59, 62, 65, 66, 69, 70, 81, 85, 88, 89,

B 59, 62, 65, 66, 69, 70, 81, 85, 88, 89,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 43, 44, 46, 56, 57, 58, 86, 92, 93, 96, 97, 100, 119, 122, 129, 130, 133, 136, 137, 211,

B 43, 44, 46, 56, 57, 58, 86, 92, 93, 96, 97, 100, 119, 122, 129, 130, 133, 136, 137,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:3CBU B:3CBU

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 3CBU.ali
atm file: 3CBU.atm
cof file: 3CBU.cof
hbd file: 3CBU.hbd
html file: 3CBU.html
pdb file: 3CBU.pdb
ps file: 3CBU.ps
psa file: 3CBU.psa
rtf file: 3CBU.rtf
sst file: 3CBU.sst
tem file: 3CBU.tem