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Pfam Domains mapped on to the structure: 3C6F

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD
1 A PF04239 Protein of unknown function (DUF421) PF04239 PF04239

Conserved Domain Database Superfamily Annotations: 3C6F

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD
1 3C6F 207274 DUF421 superfamily N -
Structural Details of PDB entry 3C6F

Structural Details of PDB entry 3C6F

PDBid Chains Hinge Swapped Domain
3C6F A,D,C,B A:54-58,D:54-58,C:54-58,B:54-58 A:94-153,D:94-153,C:94-153,B:94-153

Swapped-domain interface residues and interactions:

Chains Residues
A 101, 103, 105, 106, 115, 116, 119, 128, 129, 130, 131, 132, 152, 170, 228, 229,
C 101, 102, 103, 105, 106, 115, 116, 119, 128, 129, 130, 131, 170, 228,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 169, 172, 175, 176, 210, 211, 213, 215, 221, 223, 227, 230,
C 169, 172, 175, 176, 210, 211, 213, 215, 218, 221, 223, 229,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain
ANo mutationNo mutationNo mutationMET(121)LEU, MET(138)LEU,
DNo mutationNo mutationNo mutationMET(121)LEU, MET(138)LEU,
CNo mutationNo mutationNo mutationMET(121)LEU, MET(138)LEU,
BNo mutationNo mutationNo mutationMET(121)LEU, MET(138)LEU,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

Jmol_logo            Jmol_logo            Jmol_logo

2D-plot:

A:3C6F B:3C6F C:3C6F D:3C6F

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file:3C6F.ali
atm file:3C6F.atm
cof file:3C6F.cof
hbd file:3C6F.hbd
html file:3C6F.html
pdb file:3C6F.pdb
ps file:3C6F.ps
psa file:3C6F.psa
rtf file:3C6F.rtf
sst file:3C6F.sst
tem file:3C6F.tem