3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 3C24

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase PF03446 PF03446

Conserved Domain Database Superfamily Annotations: 3C24

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 3C24 212616 NADB_Rossmann superfamily C -

2 3C24 212616 NADB_Rossmann superfamily C -

Structural Details of PDB entry 3C24

Structural Details of PDB entry 3C24

PDBid Chains Hinge Swapped Domain

3C24 A,B A:262-265,B:262-265 A:249-261,B:249-261

Swapped-domain interface residues and interactions:

Chains Residues
A 127, 128, 150, 200, 224, 249, 250, 252, 253, 256, 257, 258, 259, 260, 261, 264, 268, 278, 281, 282,

B 127, 128, 195, 200, 219, 224, 249, 252, 253, 256, 257, 258, 259, 260, 261, 263, 266, 268, 269, 282,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 121, 123, 124, 125, 126, 129, 132, 137, 140, 141, 148, 177, 179, 181, 185, 188, 189, 193, 194, 195, 197, 198, 201, 202, 203, 204, 206, 207, 208, 209, 211, 212, 216, 217, 218, 219, 221, 222, 223, 225, 226, 228, 229, 230, 231, 232, 233, 234, 235, 236, 238, 239, 241, 242, 245, 262, 263, 266, 267, 269, 270, 271, 272, 274, 277, 284,

B 76, 121, 123, 124, 125, 126, 129, 130, 132, 137, 140, 141, 148, 150, 177, 179, 181, 185, 188, 189, 193, 194, 197, 198, 201, 202, 203, 204, 206, 207, 208, 209, 211, 212, 216, 217, 218, 221, 222, 223, 225, 226, 228, 229, 230, 231, 232, 233, 234, 235, 236, 238, 239, 241, 242, 245, 262, 264, 267, 270, 271, 272, 274, 277, 278, 281,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:3C24 B:3C24

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 3C24.ali
atm file: 3C24.atm
cof file: 3C24.cof
hbd file: 3C24.hbd
html file: 3C24.html
pdb file: 3C24.pdb
ps file: 3C24.ps
psa file: 3C24.psa
rtf file: 3C24.rtf
sst file: 3C24.sst
tem file: 3C24.tem