3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 3BT2

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00051 Kringle domain PF00051 PF00051

2 B PF01033 Somatomedin B domain PF01033 PF01033

3 L PF13895 Immunoglobulin domain PF13895 PF13895

4 L PF00047 Immunoglobulin domain PF00047 PF00047

5 H PF13895 Immunoglobulin domain PF13895 PF13895

6 U PF00021 u-PAR/Ly-6 domain PF00021 PF00021

7 U PF00021 u-PAR/Ly-6 domain PF00021 PF00021

8 U PF00021 u-PAR/Ly-6 domain PF00021 PF00021

Gene Ontology Annotations: 3BT2

No. GO ID GO Description Linkout - AmiGO

1 GO:0006955 immune response GO:0006955

Conserved Domain Database Superfamily Annotations: 3BT2

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 3BT2 29016 cd00117 LU - cl10471

2 3BT2 209150 cl10471 LU superfamily - -

3 3BT2 29016 cd00117 LU - cl10471

4 3BT2 209150 cl10471 LU superfamily - -

5 3BT2 209150 cl10471 LU superfamily - -

Structural Details of PDB entry 3BT2

Structural Details of PDB entry 3BT2

PDBid Chains Hinge Swapped Domain

3BT2 H,L H:42-46,L:41-45 H:1-41,L:1-40

Swapped-domain interface residues and interactions:

Chains Residues
H 39,

L 34, 36, 38,

Non-swapped-domain interface residues and interactions:

Chains Residues
H 44, 45, 47, 58, 89, 91, 95, 98, 99, 100, 101, 103, 104, 105, 122, 123, 124, 125, 126, 132, 136, 138, 156, 159, 160, 161, 162, 164, 165, 166, 171, 173, 175, 203,

L 41, 43, 44, 46, 49, 50, 53, 87, 89, 91, 93, 94, 96, 98, 100, 113, 115, 117, 118, 120, 122, 123, 126, 130, 132, 134, 136, 137, 159, 160, 161, 162, 163, 166, 173, 175, 177, 179, 212,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

H No mutation No mutation No mutation No mutation

L No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:3BT2

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 3BT2.ali
atm file: 3BT2.atm
cof file: 3BT2.cof
hbd file: 3BT2.hbd
html file: 3BT2.html
pdb file: 3BT2.pdb
ps file: 3BT2.ps
psa file: 3BT2.psa
rtf file: 3BT2.rtf
sst file: 3BT2.sst
tem file: 3BT2.tem