Pfam Domains mapped on to the structure: 3BCP

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00074	Pancreatic ribonuclease	PF00074	PF00074

Conserved Domain Database Superfamily Annotations: 3BCP

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	3BCP	119387	cd06265	RNase_A_canonical -	cl00128
2	3BCP	206850	cl00128	RNase_A	superfamily - -

Structural Details of PDB entry 3BCP PDBid Chains Hinge Swapped Domain 3BCP A,D,C,B A:16-22,D:16-22,C:16-22,B:16-22 A:1-15,D:1-15,C:1-15,B:1-15 Swapped-domain interface residues and interactions: Chains Residues A 4, 5, 8, 9, 10, 11, 12, 13, 14, 15, 33, 45, 46, 47, 48, 49, 50, 51, 116, 117, 118, B 4, 5, 8, 9, 10, 11, 12, 13, 14, 15, 33, 45, 46, 47, 48, 49, 51, 116, 117, 118, Non-swapped-domain interface residues and interactions: Chains Residues A 17, 18, 19, 21, 22, 25, 29, 34, 35, 41, 44, 54, 80, 101, 120, 124, B 17, 18, 19, 21, 22, 25, 29, 34, 35, 41, 44, 54, 80, 101, 103, 120,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	ALA(19)PRO,	No mutation	ALA(19)PRO,	No mutation
D	ALA(19)PRO,	No mutation	No mutation	No mutation
C	ALA(19)PRO,	No mutation	No mutation	No mutation
B	ALA(19)PRO,	No mutation	ALA(19)PRO,	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:3BCP

B:3BCP

C:3BCP

D:3BCP

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	3BCP.ali
atm file:	3BCP.atm
cof file:	3BCP.cof
hbd file:	3BCP.hbd
html file:	3BCP.html
pdb file:	3BCP.pdb
ps file:	3BCP.ps
psa file:	3BCP.psa
rtf file:	3BCP.rtf
sst file:	3BCP.sst
tem file:	3BCP.tem