Pfam Domains mapped on to the structure: 3B5K

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF02025	Interleukin 5	PF02025	PF02025

Gene Ontology Annotations: 3B5K

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0005576	extracellular region	GO:0005576

Conserved Domain Database Superfamily Annotations: 3B5K

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	3B5K	202094	cl03408	IL5	superfamily - -

Structural Details of PDB entry 3B5K PDBid Chains Hinge Swapped Domain 3B5K A,B A:87-89,B:87-89 A:90-111,B:90-110 Swapped-domain interface residues and interactions: Chains Residues A 8, 11, 15, 26, 31, 32, 33, 34, 35, 41, 90, 91, 92, 93, 94, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 110, 111, B 8, 11, 15, 26, 29, 31, 32, 33, 34, 35, 41, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, Non-swapped-domain interface residues and interactions: Chains Residues A 18, 22, 25, 28, 29, 36, 37, 38, 39, 40, 42, 43, 44, 45, 47, 48, 52, 55, 72, 75, 78, 79, 82, 83, 85, 86, 87, 89, B 7, 14, 18, 22, 25, 28, 36, 37, 38, 39, 40, 42, 43, 44, 45, 46, 47, 48, 51, 52, 54, 55, 72, 75, 78, 79, 82, 83, 85, 86, 87, 89,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	LEU(31)MET, LEU(107)MET,	No mutation	LEU(107)MET,
B	No mutation	LEU(31)MET, LEU(107)MET,	THR(7)MET,	LEU(107)MET,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:3B5K

B:3B5K

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	3B5K.ali
atm file:	3B5K.atm
cof file:	3B5K.cof
hbd file:	3B5K.hbd
html file:	3B5K.html
pdb file:	3B5K.pdb
ps file:	3B5K.ps
psa file:	3B5K.psa
rtf file:	3B5K.rtf
sst file:	3B5K.sst
tem file:	3B5K.tem