Pfam Domains mapped on to the structure: 2ZNH
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00079
Serpin (serine protease inhibitor)
PF00079
PF00079
Conserved Domain Database Superfamily Annotations: 2ZNH
Structural Details of PDB entry 2ZNH
Structural Details of PDB entry 2ZNH
PDBid
Chains
Hinge
Swapped Domain
2ZNH
A,B
A:336-341,B:336-341;A:379-408,B:379-408
A:342-378,B:342-378
Swapped-domain interface residues and interactions:
Chains
Residues
A
20 , 77 , 78 , 79 , 93 , 94 , 95 , 96 , 98 , 153 , 154 , 155 , 158 , 197 , 198 , 201 , 202 , 224 , 225 , 228 , 229 , 231 , 252 , 322 , 323 , 324 , 325 , 326 , 327 , 328 , 329 , 330 , 331 , 332 , 342 , 343 , 344 , 350 , 351 , 352 , 353 , 354 , 355 , 356 , 359 , 362 , 365 , 366 , 367 , 368 , 369 , 370 , 371 , 372 , 373 , 374 , 375 , 376 , 377 , 378 ,
B
20 , 77 , 78 , 79 , 93 , 94 , 95 , 96 , 98 , 153 , 154 , 155 , 158 , 197 , 198 , 201 , 202 , 224 , 225 , 228 , 229 , 231 , 322 , 323 , 324 , 325 , 326 , 327 , 328 , 329 , 330 , 331 , 332 , 342 , 343 , 344 , 350 , 351 , 352 , 353 , 354 , 355 , 356 , 359 , 362 , 365 , 366 , 367 , 368 , 369 , 370 , 371 , 372 , 373 , 374 , 375 , 376 , 377 , 378 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
26 , 82 , 83 , 86 , 87 , 90 , 97 , 101 , 102 , 105 , 152 , 200 , 203 , 206 , 210 , 211 , 212 , 213 , 214 , 215 , 216 , 217 , 219 , 220 , 221 , 222 , 223 , 234 , 281 , 302 , 335 , 336 , 337 , 339 , 340 , 341 , 379 , 380 , 381 , 382 , 383 , 384 , 385 , 386 , 387 , 388 , 389 , 390 , 391 , 392 , 393 , 412 , 422 , 430 ,
B
26 , 82 , 83 , 86 , 87 , 90 , 97 , 101 , 102 , 105 , 152 , 176 , 200 , 203 , 206 , 210 , 211 , 212 , 213 , 214 , 215 , 216 , 217 , 218 , 219 , 220 , 221 , 222 , 223 , 252 , 281 , 335 , 336 , 337 , 338 , 339 , 340 , 341 , 379 , 380 , 381 , 382 , 383 , 384 , 385 , 386 , 387 , 388 , 389 , 390 , 391 , 392 , 393 , 412 , 422 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: